Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study was conducted to investigate the effects of daily supplementation of fermented ginseng powder on improvement of Liver function.
The investigators performed a 12-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of fermented ginseng powder on improvement of Liver function. The investigators measured ALT(Alanine Transaminase) profiles, Liver function index, fatty liver grade, lipid metabolism index, total antioxidant capacity, imflammation index, and Multidimensional Fatigue Scale.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| fermented ginseng powder | Experimental | tablets (2 tablets/day, 125 mg & 500 mg/day) for 12 weeks. |
|
| Placebo | Placebo Comparator | Placebo for 12 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| fermented ginseng powder | Dietary Supplement | tablets (2 tablets/day, 125 mg & 500 mg/day) for 12 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes of ALT(Alanine Transaminase) | Changes of ALT were assessed before and after the intervention | Baseline and 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Changes of Liver function index | Changes of AST were assessed before and after the intervention | Baseline and 12 weeks |
| Changes of fatty liver grade | Changes of fatty liver grade were assessed before and after the intervention |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Under antipsychotic drugs therapy within past 2 months
History of alcohol or substance abuse
Participation in any other clinical trials within past 2 months
Laboratory test by show the following results
Pregnancy or breast feeding etc.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Trial Center for Functional Foods Chonbuk National University Hospital | Jeonju | Jeollabuk-do | 54907 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32425736 | Derived | Jung SJ, Hwang JH, Park SH, Choi EK, Ha KC, Baek HI, Shin DG, Seo JH, Chae SW. A 12-week, randomized, double-blind study to evaluate the efficacy and safety of liver function after using fermented ginseng powder (GBCK25). Food Nutr Res. 2020 Apr 6;64. doi: 10.29219/fnr.v64.3517. eCollection 2020. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D065626 | Non-alcoholic Fatty Liver Disease |
| D005234 | Fatty Liver |
| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Placebo | Dietary Supplement | Placebo for 12 weeks. |
|
| Baseline and 12 weeks |
| Changes of lipid metabolism index | Changes of lipid metabolism index were assessed before and after the intervention | Baseline and 12 weeks |
| Changes of total antioxidant capacity | Changes of total antioxidant capacity were assessed before and after the intervention | Baseline and 12 weeks |
| Changes of imflammation index | Changes of imflammation index were assessed before and after the intervention | Baseline and 12 weeks |
| Changes of Multidimensional Fatigue Scale | Changes of Multidimensional Fatigue Scale were assessed before and after the intervention | Baseline and 12 weeks |