A Human Trial to Evaluate the Efficacy and Safety of Fermented Turmeric in Subjects Showing Mild Hepatic Injury

The investigators performed a double-blind parallel study in a group of showing mild hepatic injury subjects who were given Fermented turmeric over a period of 12 weeks. The investigators measured liver function parameters , including ALT(Alanine Transaminase), AST(Aspartate Transaminase), ALP(Alkaline Phosphatase), γ-GT(Gamma-Glutamyl Transferase), and serum bilirubin, and monitored their blood pressure.

Inclusion Criteria:

• Males and females 19-70 years old
• Mild hepatic injury as indicated by ALT(Alanine Transaminase) level ≥ 40
• Able to give informed consent

Exclusion Criteria:

• Allergy or hypersensitivity to any of the ingredients in the test products
• History of reaction to any of the experimental products or of gastrointestinal diseases such as Crohn's disease or gastrointestinal surgery
• Carriers of viral hepatitis (type B and C)
• History of underlying Esophageal varices, hepatic encephalopathy, ascites(past 12 months)
• Participation in other clinical trials within the past 2 months
• Patients with acute hepatitis (type B and C)
• History of underlying cirrhosis and liver cancer
• History of underlying biliary diseases such as jaundice or gallstones
• History of underlying kidney disease such as Chronic renal failure or nephrotic syndrome
• Pregnant, planning to become pregnant, or breast-feeding
• Laboratory test, medical or psychological conditions deemed by the investigators to interfere with successful participation in the study