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In this protocol registration, the investigators plan a secondary data analysis of a dataset to explore the effects of intra-nasal oxytocin on the non-verbal expression of affiliation.
Using Liu et al.'s (2012) dataset, the investigators seek to observe whether the administration of oxytocin modifies non-verbal communication with a stranger.
This dataset involves a conversation between two strangers that took place 45 minutes after drug administration. While Liu et al. coded the video for markers of interpersonal distance (physical distance, eye contact, conversational intimacy), the investigators seek to analyse oxytocin's effects on non-verbal communication of affiliative and sexual cues (e.g., smiles, lip puckers). Based on findings that oxytocin's effects depend on context, the investigators will explore these relationships as a function of the conversational context (where participants converse with each other using low-, medium-, and high-intimacy topics, or in an unstructured conversation).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oxytocin | Experimental | 24IU Syntocinon, delivered in a single nose via a nasal spray |
|
| Placebo | Placebo Comparator | Matched nasal spray |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oxytocin | Drug | Administration of the hormone oxytocin |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Non-verbal communication | Based on coding the video-recorded interaction between two strangers, using a coding scheme by Gonzaga et al. (for affiliative and sexual cues) | Measured in the interaction which commenced 45mins after drug administration |
| Measure | Description | Time Frame |
|---|---|---|
| Ratings of the person participants interacted with | Positivity or sexual attraction towards the other participant in the conversation (as measured using visual analogue scales based on person perception studies) | Measured following the interaction (which commenced 45 mins after drug administration) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of New South Wales | Sydney | New South Wales | 2052 | Australia |
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| ID | Term |
|---|---|
| D010121 | Oxytocin |
| ID | Term |
|---|---|
| D010909 | Pituitary Hormones, Posterior |
| D010907 | Pituitary Hormones |
| D036361 | Peptide Hormones |
| D006728 | Hormones |
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| Placebos | Drug |
|
| D006730 |
| Hormones, Hormone Substitutes, and Hormone Antagonists |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |