Korean Cardiac Arrest Research Consortium | NCT03222999

Studies
Korean Cardiac Arrest Research Consortium

NCT03222999

Sponsor

Korean Cardiac Arrest Research Consortium

Status

Recruiting

Last Update Posted

Mar 6, 2025Actual

Enrollment

30,000Estimated

Phase

Not provided

Conditions

Out-of-Hospital Cardiac Arrest

Interventions

No intervention planned

Countries

South Korea

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Mar 2025

Overall Recruitment Status or Expanded Access Status

Recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Oct 1, 2015Actual

Primary Completion Date

Dec 31, 2028Estimated

Completion Date

Dec 31, 2028Estimated

First Submitted Date

Jul 6, 2017

First Submission Date that Met QC Criteria

Jul 17, 2017

First Posted Date

Jul 19, 2017Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Mar 4, 2025

Last Update Posted Date

Mar 6, 2025Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

Chung, Sung-Phil, Study Chair, Korean Cardiac Arrest Research ConsortiumPrincipal Investigator

Lead Sponsor

Korean Cardiac Arrest Research ConsortiumOTHER

Collaborators

Not provided

Oversight Module

Has Data Monitoring Committee (DMC)

Yes

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

FDAAA801 Violation

Not provided

Description Module

Brief Summary

This study will evaluated the epidemiology and the outcomes of patients suffering out-of-hospital cardiac arrest with presumed cardiac etiology in Korea.

Detailed Description

The Korean Cardiac Arrest Research Consortium (KoCARC) is a collaborative research network developed to comprehend various researches conducted in the field of out-of-cardiac arrest resuscitation and to strengthen the cooperative effort in conducting studies. It was organized in 2014 with recruitment of hospitals willing to participate voluntarily to the consortium.

Not only for emergency medicine, but KoCARC is expanding the research collaboration with cardiology, preventive medicine and epidemiology as well. To enhance the professionalism and effectiveness in research, seven research committees, which consists of Epidemiology and Preventive Research Committee (EPR), Community Resuscitation Research Committee (CRR), EMS Resuscitation Research Committee (ERR), Hospital Resuscitation Research Committee (HRR), Hypothermia and Post-resuscitation Care Research Committee (HPR), Cardiac Care Resuscitation Committee (CCR) and Pediatric Resuscitation Research Committee (PRR). Also Data Safety and Monitoring Board Committee (DSMB) is organized to provide annual review and Security and Ethics Committee to oversight security and ethical issues in research. Monthly meeting of interdisciplinary steering committee, consists of the consortium chair, steering committee chair, each research committee chair and secretary committee, is held to approve the proposed research agendas and to mediate between multi-center trial participating hospitals.

KoCARC registry is a data collecting system composed of OHCA risk and prognostic variables developed to provide the platform to researches conducted in KoCARC.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Yes

Target Follow-Up Duration

6 Months

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

30,000Estimated

Arms/Interventions Module

Arm Groups

Not provided

Interventions

Name	Type	Description	Arm Group Labels	Other Names
No intervention planned	Other	No intervention planned

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Survival at 6 month	Patients will be followed upon hospital discharge and up to 6 month.	6 months after cardiac arrest

Secondary Outcomes

Measure	Description	Time Frame
Good neurological recovery at 6 month	Good neurological recovery: Cerebral Performance Category (CPC) 1 or 2. Patients will be followed upon hospital discharge and up to 6 month.	6 months after cardiac arrest

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

OHCA patients who were transported to participating emergency department (ED) by emergency medical service with resuscitation efforts and whose arrest was identified as a presumed cardiac etiology by emergency physicians in ED.

Exclusion Criteria:

OHCA with terminal illness documented by medical record, under hospice care, with pregnancy, with pre-documented 'Do Not Resuscitate' card
OHCA of definite non-cardiac etiology, including trauma, drowning, poisoning, burn, asphyxia, or hanging

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

Not provided

Maximum Age

Not provided

Standard Ages

ChildAdultOlder Adult

Study Population

EMS treated OHCA who visits study participating ED

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
KoCARC Coordination Center	Contact	82-2-2072-4052		kocarc_cc@naver.com
Yeongho Choi, MD	Contact	82-10-4657-9113		d2uk87@gmail.com

Overall Officials

Name	Affiliation	Role
Sung-Pil Chung, MD, PhD	Korean Cardiac Arrest Resuscitation Consortium	Study Chair

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Korean Cardiac Arrest Resuscitation Consortium	Recruiting	Seoul		03080	South Korea

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
40461141	Derived	Choi A, Park I, You JS, Chung SP, Park YS. Non-Linear Relationship Between Alcohol Consumption and Neurological Outcomes in Patients With Out-of-Hospital Cardiac Arrest Presenting to the Emergency Department. J Korean Med Sci. 2025 Jun 2;40(21):e96. doi: 10.3346/jkms.2025.40.e96.
39516448	Derived	Lee SH, Cho Y, Oh J, Kang H, Lim TH, Ko BS, Yoo KH, Lee J. Total cholesterol and bilirubin levels are associated with neurologic outcomes in patients with out-of-hospital cardiac arrest. Intern Emerg Med. 2025 Jun;20(4):1185-1193. doi: 10.1007/s11739-024-03742-0. Epub 2024 Nov 8.

ID	Term
D006323	Heart Arrest
D006331	Heart Diseases
D002318	Cardiovascular Diseases