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| Name | Class |
|---|---|
| Helios Health Institute GmbH | OTHER |
| Heart Center Leipzig - University Hospital | OTHER |
| IHF GmbH - Institut für Herzinfarktforschung | OTHER |
| Universitätsklinikum Hamburg-Eppendorf |
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In Germany, 70.000 to 100.000 patients suffer from out-of-hospital cardiac arrest (OHCA) every year. More than half of these are due to cardiac causes. Despite the medical progress over the last decades, rates of survival with good neurological outcome remain low. For many below-mentioned issues, no adequate evidence from randomized trials is available. Therefore, a systematic and standardized recording of the pre-clinical, clinical and post-clinical treatment course and of the clinical outcomes of OHCA patients is essential to improve patient care. Aim of the German Cardiac Arrest Registry (G-CAR) is to achieve a better understanding of the disease entity, leading to an optimized treatment of OHCA patients. The recorded data include information on demographic and psychosocial aspects, course of the disease, clinical, laboratory and other examinations as well as treatment modalities in patients with OHCA due to a cardiac cause.
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| Measure | Description | Time Frame |
|---|---|---|
| In hospital mortality | until discharge, an average of 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Length of ICU stay | until discharge, an average of 2 weeks | |
| Length of hospital stay | until discharge, an average of 2 weeks | |
| Mortality |
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Inclusion Criteria:
Exclusion Criteria:
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patients with out-of-hospital cardiac arrest with assumed cardiovacular cause
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Janine Pöss, Dr. | Contact | +49 341 865 | 1428 | janine.poess@medizin.uni-leipzig.de |
| Holger Thiele, Prof. | Contact | +49 341 865 | 1428 | holger.thiele@medizin.uni-leipzig.de |
| Name | Affiliation | Role |
|---|---|---|
| Janine Pöss, Dr. | Heart Center Leipzig at University of Leipzig, Department of Internal Medicine/Cardiology | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHARITE - Universitätsmedizin Berlin - Campus Virchow Klinikum | Active, not recruiting | Berlin | State of Berlin | 13353 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38869632 | Derived | Poss J, Sinning C, Rossberg M, Hosler N, Ouarrak T, Bottiger BW, Ewen S, Wienbergen H, Voss F, Dutzmann J, Tigges E, Voigt I, Freund A, Desch S, Michels G, Thiele H, Zeymer U; G-CAR Investigators. German Cardiac Arrest Registry (G-CAR)-results of the pilot phase. Clin Res Cardiol. 2025 Oct;114(10):1270-1279. doi: 10.1007/s00392-024-02468-5. Epub 2024 Jun 13. | |
| 35729429 |
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| ID | Term |
|---|---|
| D058687 | Out-of-Hospital Cardiac Arrest |
| ID | Term |
|---|---|
| D006323 | Heart Arrest |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| OTHER |
| St. Antonius Hospital | OTHER |
| Klinikum Ludwigshafen | OTHER |
| University of Magdeburg | OTHER |
| Charite University, Berlin, Germany | OTHER |
| University Hospital of Cologne | OTHER |
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| Day 30 |
| Mortality | Month 6 |
| European Quality of Life 5 Dimensions 5 Level Version (EQ-5D) | five levels in each dimension are worded as (1) 'not /no problems', (2) 'slight problems', (3) 'moderate problems', (4) 'severe problems', and (5) 'unable to' | Month 6 |
| Post Traumatic Stress Syndrome | PTSS-14 | Month 6 |
| Reintegration | Reintegration to Normal Living Index | Month 6 |
| Hospital Anxiety and Depression Scale (HADS) | score 0-21; higher value show more severe depression | Month 6 |
| Mini Montreal Cognitive Assessment (MoCA) | score 0-15; 11 or higher is normal, 10 or less indicate cognitive dysfunction | Month 6 |
| Mini Montreal Cognitive Assessment (MoCA) | score 0-15; 11 or higher is normal, 10 or less indicate cognitive dysfunction | Month 12 |
| Mortality | Month 12 |
| European Quality of Life 5 Dimensions 5 Level Version (EQ-5D) | five levels in each dimension are worded as (1) 'not /no problems', (2) 'slight problems', (3) 'moderate problems', (4) 'severe problems', and (5) 'unable to' | Month 12 |
| Post Traumatic Stress Syndrome (PTSS-14) | scor 14-98; higher value indicate more post traumatic stress | Month 12 |
| Reintegration | Reintegration to Normal Living Index | Month 12 |
| Hospital Anxiety and Depression Scale (HADS) | score 0-21; higher value indicate more severe depression | Month 12 |
| SLK-Kliniken Heilbronn - Klinikum am Plattenwald | Recruiting | Bad Friedrichshall | 74177 | Germany |
|
| Charité Universitätsmedizin Berlin - Deutsches Herzzentrum Berlin | Recruiting | Berlin | 12203 | Germany |
|
| Universitätsklinikum Bonn | Recruiting | Bonn | Germany |
|
| Bremer Institut für Herz- und Kreislaufforschung am Klinikum Links der Weser | Recruiting | Bremen | 28277 | Germany |
|
| Herzzentrum der Universität zu Köln | Recruiting | Cologne | 50937 | Germany |
|
| Herzzentrum Dresden GmbH | Active, not recruiting | Dresden | 01307 | Germany |
| Universitätsklinikum Düsseldorf - Klinik für Kardiologie, Pneumologie und Angiologie | Recruiting | Düsseldorf | 40225 | Germany |
|
| Elisabeth Krankenhaus Essen - Klinik für Akut- und Notfallmedizin | Recruiting | Essen | 45138 | Germany |
|
| Klinikum Frankfurt Höchst | Recruiting | Frankfurt | 65929 | Germany |
|
| Universitätsklinikum Halle (Saale) | Recruiting | Halle | 06120 | Germany |
|
| Universitäres Herz- und Gefäßzentrum Hamburg | Recruiting | Hamburg | 20246 | Germany |
|
| Asklepios Klinik St- Georg Hamburg | Recruiting | Hamburg | Germany |
|
| SLK-Kliniken Heilbronn - Klinikum am Gesundbrunnen | Recruiting | Heilbronn | 74078 | Germany |
|
| Universitätsklinikum des Saarlandes | Recruiting | Homburg | Germany |
|
| Heart Center Leipzig at University of Leipzig, Department of Internal Medicine/Cardiology | Recruiting | Leipzig | 04289 | Germany |
|
| Klinikum der Stadt Ludwigshafen gGmbH | Recruiting | Ludwigshafen | 67063 | Germany |
|
| Herzzentrum Lübeck | Recruiting | Lübeck | Germany |
|
| Universitätsklinikum Mannheim | Recruiting | Mannheim | 68167 | Germany |
|
| Klinikum der Universität München | Recruiting | München | 81377 | Germany |
|
| Marienhaus Klinikum Hetzelstift | Recruiting | Neustadt | 67434 | Germany |
|
| Hegau-Bodensee Klinikum | Recruiting | Singen | 78224 | Germany |
|
| Hegau-Bodensee-Klinikum Singen | Not yet recruiting | Singen | 78224 | Germany |
|
| Schwarzwald-Baar Klinikum VS | Recruiting | Villingen-Schwenningen | 78052 | Germany |
|
| Dr. Horst Schmidt Kliniken | Active, not recruiting | Wiesbaden | Germany |
| Poss J, Sinning C, Schreiner I, Apfelbacher C, Drewitz KP, Hosler N, Schneider S, Pieske B, Bottiger BW, Ewen S, Wienbergen H, Kelm M, Bock D, Graf T, Adler C, Dutzmann J, Knie W, Orban M, Zeymer U, Michels G, Thiele H; G-CAR Investigators. German Cardiac Arrest Registry: rationale and design of G-CAR. Clin Res Cardiol. 2023 Apr;112(4):455-463. doi: 10.1007/s00392-022-02044-9. Epub 2022 Jun 21. |