Efficacy Transverse Abdominal Plane (TAP) Block Renal Transplant Surgery

Efficacy of Ultrasound-guided Transverse Abdominal Plane Block for Analgesia in Renal Transplantation

The objective of this study is to evaluate the efficacy and safety of transverse abdominal plane block in patients undergoing renal transplant surgery.Adult renal transplant recipients will be prospectively randomized to receive a standard general anesthetic technique supplemented with ropivacaine 0.375% 20 mL TAP block or sham block with 20 mL 0.9% saline. Both groups will receive patient-controlled morphine analgesia. Patient assessment will occur in the postanesthetic care unit and at 1, 2, 4, 6, 12, and 24 hours. The primary outcome is total morphine consumption in the first 24 hours after renal transplantation. Other outcomes asses include pain scores, presence of nausea or vomiting, excessive sedation, and respiratory depression.

Inclusion Criteria:

• end-stage renal disease undergoing cadaveric renal transplantation

Exclusion Criteria:

• Contraindications to the use of morphine
• Contraindications to the use ropivacaine
• Peripheral neuropathy
• Inability to use a Patient Control Analgesia device