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| Name | Class |
|---|---|
| Guang'anmen Hospital of China Academy of Chinese Medical Sciences | OTHER |
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This study evaluates the clinical efficacy of Gualou Xiebai Banxia Decoction compounded with Danshen Decoction in the treatment of unstable angina pectoris. All of the patients will be divided into 2 arms randomly. One of the arms will be treated by conventional western medicine, the other one will be treated by Gualou Xiebai Banxia Decoction compounded with Danshen Decoction at the base of conventional western medicine.
Gualou Xiebai Banxia Decoction compounded with Danshen Decoction has the effect of promoting blood circulation and resolving phlegm, so it will be used for patients taht belong to phlegm and blood stasis type.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Phlegm and blood stasis | Experimental | Patients in this group will be treated by Gualou Xiebai Banxia Decoction & Danshen Decoction at the base of conventional western medicine. |
|
| Conventional western medicine | Other | Patients in this group will be treated by conventional western medicine, including anti-platelet drugss,lipid regulating drugs, coronary vasodilator, etc. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Anti-Platelet Drugs | Drug | Including aspirin and clopidogrel, etc. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | Death caused by cardiovascular disease | Six months after drug intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Myocardial enzymes | The unit is mmol/L | At baseline and 4 weeks after drug intervention |
| lood lipid The unit is mmol/L. Blood lipid | The unit is mmol/L. |
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Inclusion Criteria:
Patients have at least one of these symptoms:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Panpan Tian | Contact | +86 15652388175 | 15652388175@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Jun Li, MD | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23762142 | Result | Wang J, Yu G. A Systems Biology Approach to Characterize Biomarkers for Blood Stasis Syndrome of Unstable Angina Patients by Integrating MicroRNA and Messenger RNA Expression Profiling. Evid Based Complement Alternat Med. 2013;2013:510208. doi: 10.1155/2013/510208. Epub 2013 May 14. | |
| 22536282 | Result | Qiu Y, Xu H, Shi D. Traditional chinese herbal products for coronary heart disease: an overview of cochrane reviews. Evid Based Complement Alternat Med. 2012;2012:417387. doi: 10.1155/2012/417387. Epub 2012 Mar 28. |
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| ID | Term |
|---|---|
| D000789 | Angina, Unstable |
| ID | Term |
|---|---|
| D000787 | Angina Pectoris |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D057847 | Lipid Regulating Agents |
| C000722533 | gualou xiebai banxia decoction |
| ID | Term |
|---|---|
| D045506 | Therapeutic Uses |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
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| Lipid Regulating Drugs | Drug | Mainly including statins |
|
| Coronary Vasodilator | Drug | Mainly including nitrates |
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| Gualou Xiebai Banxia Decoction & Danshen Decoction | Drug | Mainly including Fructus Trichosanthis, Rhizoma Pinelliae, Allium, Salvia Miltiorrhiza etc. |
|
| At baseline and 4 weeks after drug intervention |
| Treadmill exercise test | The result will be positive or negative. | At baseline and 4 weeks after drug intervention |
| The incidence of myocardial infarction or heart failure | Six months after drug intervention] Inclusion Criteria: |
| 27777598 | Result | Liu W, Xiong X, Yang X, Chu F, Liu H. The Effect of Chinese Herbal Medicine Gualouxiebaibanxia Decoction for the Treatment of Angina Pectoris: A Systematic Review. Evid Based Complement Alternat Med. 2016;2016:8565907. doi: 10.1155/2016/8565907. Epub 2016 Sep 29. |
| 23737852 | Result | Wang J, Yang X, Chu F, Chen J, He Q, Yao K, Teng F, Gao Y, Xing Y, Wu A, Xing Y. The effects of xuefu zhuyu and shengmai on the evolution of syndromes and inflammatory markers in patients with unstable angina pectoris after percutaneous coronary intervention: a randomised controlled clinical trial. Evid Based Complement Alternat Med. 2013;2013:896467. doi: 10.1155/2013/896467. Epub 2013 May 8. |
| D014652 |
| Vascular Diseases |
| D002637 | Chest Pain |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |