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This study evaluated the association between HMGB1 and diastolic dysfunction in hypertensive patients. HMGB1 level were tested in all patients, and diastolic function determined by echocardiographic.
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| Measure | Description | Time Frame |
|---|---|---|
| Differences of HMGB1 levels between hypertensive patients with and without diastolic dysfunction | Blood samples of all individuals are collected on the day of admission and HMGB1 levels are tested. Echocardiographic assessment is performed with echocardiography device by using 2.5-3.5 Mega Hertz(MHz) transducer in the lateral decubitis position. | on the day of admission |
| Measure | Description | Time Frame |
|---|---|---|
| Differences of HMGB1 levels between grades of diastolic dysfunction | Blood samples of all individuals are collected on the day of admission and HMGB1 levels are tested. Echocardiographic assessment is performed with echocardiography device by using 2.5-3.5 Mega Hertz(MHz) transducer in the lateral decubitis position. | on the day of admission |
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Inclusion Criteria:
All of the hypertensive patients in both diastolic dysfunction and control groups were either newly diagnosed or were aware of hypertension without using any pharmacotherapy.
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Exclusion Criteria:
Individuals already under treatment for hypertension were not include.
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The study sample is recruited from the patients examined in the physical examination center of our hospital.
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| D007249 | Inflammation |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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