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| Name | Class |
|---|---|
| Laboratoire de Complexité, Innovation et Activités Motrices et Sportives | UNKNOWN |
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The inclusion of short periods of apnea (several seconds) during exercise (i.e. dynamic apnea) induces a significant decrease in blood oxygenation and muscle tissue. To date, the immediate effects ("acute apnea") of this decrease in the quantity of oxygen available at the muscle and brain level are poorly understood. Moreover, a physical training during which these short periods of apnea ("chronic apnea") would be included could lead to physiological adaptations and to improvement in physical performance similar to those obtained during altitude training.
The purpose of this study is to evaluate the effects of acute dynamic apnea on metabolism.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Apnea Group (GApn) | Experimental | Program of training with exercises including apneas |
|
| Control Group (GC) | Other | Program of training with exercises without apnea |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Program of training with exercises including apnea | Other | 16 training session on cycle ergometry with exercises including apneas. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Spectometry to measure hemoglobin rate | Measurement of oxygenation | 3 weeks |
| Wingate test to measure maximum consumption of dioxygen | Measurement of aerobic performance | 3 weeks |
| Measurement of hormonal markers | Measurement of Dehydroepiandrostenedione (DHEA) | 3 weeks |
| Jaeger debimeter system to measure of peak oxygen | Measurement of oxygen consumptiom | 3 weeks |
| Measurement of arterial saturation in dioxygen | Measurement by ear blood micro-sample | 3 weeks |
| Spectometry to measure hemoglobin | Measurement of oxygenation | 12 weeks |
| Measurement of hormonal markers | Measurement of Dehydroepiandrostenedione (DHEA) | 12 weeks |
| Jaeger debimeter system to measure of peak oxygen | Measurement of oxygen consumption, | 12 weeks |
| Measurement of arterial saturation in dioxygen |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiac frequency | measurement with a 12 lead - Electrocardiogamm | 3 weeks |
| Cardiac frequency | measurement with a 12 lead - Electrocardiogramm |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Virgile AMIOT, Ph | CHR ORLEANS | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHR d'Orléans | Orléans | 45067 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 12183481 | Background | Andersson JP, Liner MH, Runow E, Schagatay EK. Diving response and arterial oxygen saturation during apnea and exercise in breath-hold divers. J Appl Physiol (1985). 2002 Sep;93(3):882-6. doi: 10.1152/japplphysiol.00863.2001. | |
| 10677392 | Background | Caquelard F, Burnet H, Tagliarini F, Cauchy E, Richalet JP, Jammes Y. Effects of prolonged hypobaric hypoxia on human skeletal muscle function and electromyographic events. Clin Sci (Lond). 2000 Mar;98(3):329-37. |
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| ID | Term |
|---|---|
| D001049 | Apnea |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| Program of training with exercises without apnea | Other | 16 training session on cycle ergometry with exercises without apnea |
|
Measurement by ear blood micro-sample |
| 12 weeks |
| 12 weeks |
| Borg scale to measure penibility of the effort | week 3 |
| Borg scale to measure penibility of the effort | week 12 |
| 18097682 | Background | de Bruijn R, Richardson M, Schagatay E. Increased erythropoietin concentration after repeated apneas in humans. Eur J Appl Physiol. 2008 Mar;102(5):609-13. doi: 10.1007/s00421-007-0639-9. Epub 2007 Dec 19. |
| 16540709 | Background | Dufour SP, Ponsot E, Zoll J, Doutreleau S, Lonsdorfer-Wolf E, Geny B, Lampert E, Fluck M, Hoppeler H, Billat V, Mettauer B, Richard R, Lonsdorfer J. Exercise training in normobaric hypoxia in endurance runners. I. Improvement in aerobic performance capacity. J Appl Physiol (1985). 2006 Apr;100(4):1238-48. doi: 10.1152/japplphysiol.00742.2005. |
| D013568 | Pathological Conditions, Signs and Symptoms |