Acute and Chronic Effects of Dynamic Apnea in Healthy Untrained Subjects

Acute and Chronic Effects of Dynamic Apnea in Healthy Untrained Subjects

The inclusion of short periods of apnea (several seconds) during exercise (i.e. dynamic apnea) induces a significant decrease in blood oxygenation and muscle tissue. To date, the immediate effects ("acute apnea") of this decrease in the quantity of oxygen available at the muscle and brain level are poorly understood. Moreover, a physical training during which these short periods of apnea ("chronic apnea") would be included could lead to physiological adaptations and to improvement in physical performance similar to those obtained during altitude training.

The purpose of this study is to evaluate the effects of acute dynamic apnea on metabolism.

Inclusion Criteria:

• The cutaneous thickness at the vastus lateralis level lower than 1.5 cm to obtain the reliable muscle oxygenation measurement
• Subjects will have to sign the inform consent before the beginning of the study

Exclusion Criteria:

• Contraindications to regular physical exercise practice
• To practice an endurance sport more than 1h/week
• Regular practice of apnea
• Chronic use of cannabis and/or alcohol
• Cardiac or metabolic pathology
• Asthma and/or bronchodilatator treatment
• ECG abnormality at rest
• Regular consumption of tobacco