In this study, eligible patients with the medical indications (facial lipoatrophy, morphological asymmetry of the face, or debilitating scars) will be treated with Princess® VOLUME, and then will return for follow-up assessments 2, 4, 24, and 36 weeks after the treatment. A touch-up treatment may be done 2 weeks after the treatment if deemed appropriate by the Investigator.

Inclusion Criteria:

• Male or female 18 years of age or older

• Presence of a defect, which in the opinion of the Investigator can be corrected by a dermal filler, and is caused by: ° Facial lipoatrophy of moderate severity, or

  • Morphological asymmetry of the face, or
  • One or more debilitating scars on the face

• Willingness to abstain from any cosmetic or surgical procedures in the treatment area for the duration of the clinical investigation

• Willingness to take part in the clinical investigation as evidenced by a personally signed informed consent.

Exclusion Criteria:

• Pregnancy, breastfeeding, or unwillingness to use contraception throughout the clinical investigation (for women of child-bearing potential only)
• History of allergic reaction or hypersensitivity to hyaluronic acid
• History or presence of any autoimmune or connective tissue disease, or current treatment with immune therapy
• Presence of silicone implant or other non-absorbable tissue filler in the area targeted for intervention, or pre-treatment with any hyaluronic acid filler within the last six months
• Presence of infectious, inflammatory, or proliferative lesions in the area targeted for intervention
• Treatment with anticoagulant or antiplatelet drugs
• Any disease or condition which, in the Investigator's opinion, represents a safety risk for participation in the study
• Current participation in another clinical trial, or previous treatment with any investigational drug/device within 30 days prior to enrolment
• Institutionalized persons with legally limited civil rights