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Macular schisis associated with macular detachment is a one of the complications of high myopia. There is controversy in the primary treatment for this situation. This study will compare the effects of macular buckling + gas injection versus vitrectomy + internal limiting membrane peeling + gas tamponade in a cohort of highly myopic eyes with macular retinal detachment associated with macular schisis.
A randomized, open label, single center study comparing the efficacy of macular muckle + gas injection versus internal limiting membrane peeling + gas tamponade on macular schisis associated with macular detachment in eyes with high myopia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Buckle | Experimental | Macular buckling and intraocular gas (C3F8) injection. |
|
| Vitrectomy | Active Comparator | Vitrectomy, internal limiting membrane peeling, and gas tamponade (C3F8). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Macular buckling | Procedure | Surgical procedures of macular buckling, drainage of aqueous fluid (0.1-0.2 ml) through limbal paracentesis, and inject gas ( C3F8 100%, 0.2ml-0.3ml) into vitreous body through pars plana, under systemic anesthesia. |
| Measure | Description | Time Frame |
|---|---|---|
| Retinal re-attachment rate | 3 month |
| Measure | Description | Time Frame |
|---|---|---|
| Post-operative best corrected visual acuity | 12 month | |
| Post-operative macular structure on optical coherance tomography | 12 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lin Lu, MD，PhD | Zhongshan Ophthalmic Center, Sun Yat-sen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zhongshan Ophthalmic Center | Guangzhou | Guangdong | 510060 | China |
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| ID | Term |
|---|---|
| D041441 | Retinoschisis |
| ID | Term |
|---|---|
| D012162 | Retinal Degeneration |
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
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| ID | Term |
|---|---|
| D014821 | Vitrectomy |
| ID | Term |
|---|---|
| D013508 | Ophthalmologic Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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| Vitrectomy | Procedure | Surgical procedures of small gauge vitrectomy, internal limiting membrane peeling, and gas (C3F8, 14%) tamponage, under local or systemic anesthesia |
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