Effects of Macular Buckle Versus Vitrectomy on Macular Hole and Macular Detachment in Highly Myopic Eyes

A Randomized, Open Label, Single Center Study Comparing the Efficacy of Macular Buckle Versus Vitrectomy on Full-thickness Macular Hole and Concurrent Macular Detachment in Eyes With Highly Myopia

Full-thickness macular Hole associated with macular detachment is a one of the maculopathies of high myopia. There is controversy in the primary treatment for this situation. This study will compare the effects of macular buckling versus vitrectomy in a cohort of highly myopic eyes with this situation.

A randomized, open label, single center study comparing the efficacy of macular muckle + gas injection versus internal limiting membrane peeling + gas tamponade on full-thickness macular hole associated with macular detachment in eyes with high myopia.

Inclusion Criteria:

• axial length ≥ 26.5 mm or refractive error (spherical equivalent) ≥ 8.0 diopter
• full-thickness macular hole
• macular retinal detachment
• evidence of posterior staphyloma on clinical examination

Exclusion Criteria:

• macular detachment which extended to the peripheral retina (i.e., extension beyond the major vascular arcades in more than one quadrant)
• a history of vitrectomy or scleral buckling
• intraocular active hemorrhage or inflammation
• any media opacity which precluded imaging or clinical evaluation of the macula