L-carnitine for Fatigue in COPD

L-Carnitine Supplementation With and Without Health Coaching for Fatigue in Patients With Chronic Obstructive Pulmonary Disease (COPD)

supplementation with L-carnitine that is available both as an FDA-approved therapy for primary carnitine deficiency, as well as widely available as an over-the-counter ergogenic aid will improve wellbeing and function measured by questionnaires in patient with chronic obstructive pulmonary disease (COPD).

based on our review of literature that addition of health coaching (HC) to L-carnitine will yield greater gains.

Inclusion criteria:

- COPD patients with a positive screen for fatigue

Exclusion criteria:

• Vulnerable population - pregnant women, prisoners, unable to provide consent
• Pre-menopausal/breastfeeding women (pregnancy category B)
• Thyroid disease
• Anticoagulation therapy
• Decompensated cardiac disease
• Chronic Kidney Disease (CKD4 or above)
• Known seizure disorder
• Active malignancy
• Exacerbation of underlying pulmonary disease or acute illness in the 6 weeks before screening
• Enrollment in the past 6 weeks or currently in a cardiac or pulmonary rehab program or other physical fitness class(es).
• Difficulty with swallowing pills