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Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards.
To study the effectiveness of MPM in ridge augmentation with implant insertion compared with autogenous bone graft.
-PICO-
Population (P): Patients with defective maxillary alveolar ridge requiring implant insertion.
Intervention (I): Ridge augmentation with MPM.
Comparator (C): Autogenous bone graft.
Outcome (O): Patient satisfaction - Implant stability.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Autogenous bone graft (Gold Standard). | Experimental | Patients with defective maxillary alveolar ridges requiring implant insertion will have Autogenous bone graft (Gold standard) and collagen membrane to be used for bone augmentation around exposed threads of inserted dental implants. |
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| MPM Augmentation. | Active Comparator | Mineralized plasmatic matrix (MPM) to be used without collagen membrane to augment the defect in the maxillary bone and cover the exposed threads of the dental implants. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mineralized plasmatic matrix (MPM). | Other | By using venoud blood from the patient, together with bone graft, a centrifuge will be used to obtain the top layer after centrifuging blood at 3000 RPM, for 10 minutes , Which will result if sticky bone graft consistency after mixing. |
| Measure | Description | Time Frame |
|---|---|---|
| Patient Satisfaction regarding esthetic results , outcome will be measure using questionnaire. | 5 months |
| Measure | Description | Time Frame |
|---|---|---|
| Stability of dental implants , this will be measured using Ostell device in ISQ units. | 5 months. |
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Inclusion Criteria:
Exclusion Criteria:
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Evaluation of the comparative Effectiveness of MPM Augmentation in Anterior ridge defects with Autogenous bone graft.
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| ID | Term |
|---|---|
| D001862 | Bone Resorption |
| ID | Term |
|---|---|
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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| ID | Term |
|---|---|
| C083299 | 1-methyl-1-piperidinomethane sulfonate |
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| Autogenous bone graft (gold standard). | Other | Exposed implant threads are to be covered with autogenous bone and collagen membrane. |
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