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| Name | Class |
|---|---|
| Healthcare Center Tomas Rojas | OTHER |
| University of Los RÃos | UNKNOWN |
| Universidad Pública de Navarra | OTHER |
| Universidad del Rosario |
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Despite exercise training decrease blood pressure in 'average' terms, there is a wide interindividual variability after exercise training, being yet unknown what mode of exercise (e.g. endurance, strength, concurrent, or high intensity interval training) produce more/less non-responder (NR) prevalence (i.e., percentage of subjects who experienced a non-change/worsened response after training in some outcome).
Despite exercise training decrease blood pressure in 'average' terms, there is a wide interindividual variability after exercise training, being yet unknown what mode of exercise (e.g. endurance, strength, concurrent, or high intensity interval training) produce more/less non-responder (NR) prevalence (i.e., percentage of subjects who experienced a non-change/worsened response after training in some outcome).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High Intensity Interval Training | Experimental | Cycling on cycle ergometers (OXFORDTM, model BE2601, OXOFORD Inc, Santiago, Chile) for 1 min at a subjective intensity of 8-10 points of the modified Borg scale of 1-10 points, and interspersed by inactive (without movement over the bicycle) of 2 minutes as recovery period. |
|
| Control group | Active Comparator | Pre-hypertensive group was compared with healthy groups in the 2 manin variables systolic/diastolic blood pressure, as well as in other co-variables in pre-post changes. Thus, after the training intervention, and following the R and NR classification, we will compare the NR prevalence between both Pre-hypertensive and Healthy group. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High Intensity Interval Training | Behavioral | High Intensity Interval Training pre-hypertensive group; Exercise will be performed at three sessions per week. All sessions will be supervised by an exercise physiologist during 16 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in systolic blood pressure and diastolic blood pressure | After this, we calculated the delta changes in both variables and classified to all subjects in responders (R) and non-responders (NR) to decrease systolic or diastolic blood pressure. | Baseline and 16 weeks immediately after the interventions ends |
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in body mass | Baseline and 16 weeks immediately after the interventions ends | |
| Change from Baseline in body mass index | BMI will be calculated as the body weight in kilograms divided by the square of the height in meters. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cristian Alvarez | Osorno | Chile |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30405426 | Derived | Alvarez C, Ramirez-Campillo R, Cristi-Montero C, Ramirez-Velez R, Izquierdo M. Prevalence of Non-responders for Blood Pressure and Cardiometabolic Risk Factors Among Prehypertensive Women After Long-Term High-Intensity Interval Training. Front Physiol. 2018 Oct 23;9:1443. doi: 10.3389/fphys.2018.01443. eCollection 2018. |
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| ID | Term |
|---|---|
| D008659 | Metabolic Diseases |
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D000072696 | High-Intensity Interval Training |
| D035061 | Control Groups |
| ID | Term |
|---|---|
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
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| OTHER |
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| Control group | Behavioral | Moderade Intensity Interval Training pre-hypertensive group; Exercise will be performed at three sessions per week. All sessions will be supervised by an exercise physiologist during 16 weeks. |
|
| Baseline and 16 weeks immediately after the interventions ends |
| Change from Baseline in waist circumference | Baseline and 16 weeks immediately after the interventions ends |
| Change from Baseline in fat mass | Baseline and 16 weeks immediately after the interventions ends |
| Change from Baseline in heart rate at rest | Baseline and 16 weeks immediately after the interventions ends | Baseline and 16 weeks immediately after the interventions ends |
| Change from Baseline in fasting glucose | Baseline and 16 weeks immediately after the interventions ends |
| Change from Baseline in lipids | Lipid profile (low-density cholesterol, total cholesterol, high-density cholesterol and triglycerides) | Baseline and 16 weeks immediately after the interventions ends |
| Change from Baseline in one maximum repetition strength test of leg-extension exercise | Baseline and 16 weeks immediately after the interventions ends |
| D009142 |
| Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
| D015340 | Epidemiologic Research Design |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D012107 | Research Design |
| D008722 | Methods |