Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Universidad del Rosario | OTHER |
| Universidad Manuela Beltrán | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Several studies have shown relationship between exercise intensity and improvement cardiometabolic health such as body composition, endothelial function, blood pressure and blood lipids. It has been suggested that high intensity interval training and also strength or resistance training generate positive effects on metabolic risk factors, nevertheless the comparison between both types of training and their combination has not yet provided conclusive evidence. Also, it has been shown that dietary restriction has similar or more positive effects that exercise alone and the effect is greater when it is combined with exercise. For these reasons, it is necessary to clarify which type of training, in combination with a dietary restriction, is more effective to improve cardiometabolic health
The investigators hypothesized that high intensity interval, resistance training or combined training would result in similar improvements in cardiometabolic health as compared to the usual clinical care in a cohort of sedentary overweight (age 30-50 years old).
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High Intensity Interval | Experimental | Walking on a treadmill 4min at 80-90% peak heart rate and recovery 4 min at 65% peak heart rate until expenditure of 300 kcal during adaptation (first 4 weeks) and 500 kcal after week number 4 until the end of training. |
|
| Resistance training | Active Comparator | Completing a resistance circuit (including upper and lower muscle groups) as many times as needed according to subject weight until expenditure of 300 kcal during adaptation (first 4 weeks) at 20-30% of 1 one-rep max and 500 kcal after week number 4 until the end of training, at 40-60% of one-rep max. |
|
| Plus: High Intensity Interval + Resistance Training | Active Comparator | Walking on a treadmill as intervention 1 until 50% the energy expenditure prescribed is reached, then completing a resistance circuit until 100% energy expenditure is reached. Exercise will be performed at three sessions per week. |
|
| Usual clinical care | Placebo Comparator | This group will receive the usual clinical care according to the consensus recommendations of the national goals for cardiovascular health promotion and disease reduction of the American Heart Association and Colombian guidelines COLDEPORTES. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High Intensity Interval | Behavioral | Exercise will be performed at three sessions per week. All sessions will be supervised by a trained health or exercise professional. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in endothelial function as measured by flow-mediated vasodilation (FMD) | FMD will be measured using the guidelines reported by Corretti et al. The diameter of the brachial artery will be assessed using a high-resolution ultrasound device (Siemens SG-60, USA), equipped with a 7.5 MHz linear array transducer. | Baseline and 12 weeks immediately after the interventions ends |
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in body Composition as measured by Dual Energy X-ray Absorptiometry | Changes in abdominal and total adiposity (DEXA), lean tissue mass and bone mass (DEXA) the 12 weeks intervention program | Baseline and 12 weeks immediately after the interventions ends |
| Body Weight |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Robinson Ramírez Vélez, Ph.D | Universidad del Rosario | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Robinson Ramírez Vélez Ph.D | Bogotá | Cundinamarca | Colombia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28934175 | Derived | Ramirez-Velez R, Correa-Bautista JE, Gonzalez-Ruiz K, Tordecilla-Sanders A, Garcia-Hermoso A, Schmidt-RioValle J, Gonzalez-Jimenez E. The Role of Body Adiposity Index in Determining Body Fat Percentage in Colombian Adults with Overweight or Obesity. Int J Environ Res Public Health. 2017 Sep 21;14(10):1093. doi: 10.3390/ijerph14101093. | |
| 27342073 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D008659 | Metabolic Diseases |
| D050177 | Overweight |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D001835 | Body Weight |
Not provided
Not provided
| ID | Term |
|---|---|
| D000072696 | High-Intensity Interval Training |
| D055070 | Resistance Training |
| ID | Term |
|---|---|
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Resistance training | Behavioral | Exercise will be performed at three sessions per week. All sessions will be supervised by a trained health or exercise professional. |
|
| Plus: High Intensity Interval + Resistance Training | Behavioral | Exercise will be performed at three sessions per week. All sessions will be supervised by a trained health or exercise professional. |
|
| Usual clinical care | Other | Dietary restriction (1300-1500kcal) 50-52% carbohydrates, 33-35% fat, 15-20% protein |
|
| Baseline and 12 weeks immediately after the interventions ends |
| Body Mass Index | BMI will be calculated as the body weight in kilograms divided by the square of the height in meters. | Baseline and 12 weeks immediately after the interventions ends |
| Blood Pressure | Baseline and 12 weeks immediately after the interventions ends |
| Change from Baseline in peak uptake of volume of oxygen | It will be determined using a maximum treadmill exercise test (Precor TRM 885, Italy) following the modified Balke protocol | Baseline and 12 weeks immediately after the interventions ends |
| Change from Baseline in muscular fitness | Muscular fitness (MF) will be assessed using handgrip test (maximum handgrip strength assessment) using a standard adjustable handle analogue handgrip dynamometer T-18 TKK SMEDLY III® | Baseline and 12 weeks immediately after the interventions ends |
| Change from Baseline in Flexibility using the sit and reach test | Baseline and 12 weeks immediately after the interventions ends |
| Change from Baseline in LDL Cholesterol | Baseline and 12 weeks immediately after the interventions ends |
| Change from Baseline in HDL Cholesterol | Baseline and 12 weeks immediately after the interventions ends |
| Change from Baseline in Triglycerides | Baseline and 12 weeks immediately after the interventions ends |
| Change from Baseline in Glucose | Baseline and 12 weeks immediately after the interventions ends |
| Change from Baseline in Hemoglobin A1c | Baseline and 12 weeks immediately after the interventions ends |
| Change from Baseline in Quality & satisfaction with life by SF Community - short-form survey (SF-12™) Colombian version | Baseline and 12 weeks immediately after the interventions ends |
| Change from Baseline in Heart rate variability | HRV will be performed according to current recommendations by European Society of Cardiology using an evaluated share-ware | Baseline and 12 weeks immediately after the interventions ends |
| 24-hour dietary recall | Dietary data will be collected from participants on 24h of their study enrollment. Prior to administration of the 24HR, each subject received two-dimensional food models with depiction of foods and serving sizes in order to assist in reporting portion sizes of food intake. | Baseline and 12 weeks immediately after the interventions ends |
| Aortic pulse wave velocity (PWVao) and augmentation index (AIx) | PWVao and AIx will be measured with oscillometric method using the occlusion technique. | Baseline and 12 weeks immediately after the interventions ends |
| Ramirez-Velez R, Hernandez A, Castro K, Tordecilla-Sanders A, Gonzalez-Ruiz K, Correa-Bautista JE, Izquierdo M, Garcia-Hermoso A. High Intensity Interval- vs Resistance or Combined- Training for Improving Cardiometabolic Health in Overweight Adults (Cardiometabolic HIIT-RT Study): study protocol for a randomised controlled trial. Trials. 2016 Jun 24;17(1):298. doi: 10.1186/s13063-016-1422-1. |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |
| D009142 |
| Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
| D005081 | Exercise Therapy |
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
| D005791 | Patient Care |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |