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Several studies have shown relationship between exercise intensity and improvement cardiometabolic health. It has been suggested that high intensity interval training and also moderate training generate positive effects on metabolic risk factors. For these reasons, it is necessary to clarify which type of training, is more effective to improve cardiometabolic health in latinamerican population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High Intensity Interval Training | Experimental | Walking on a treadmill 4min at 80-90% peak heart rate and recovery 4 min at 65% peak heart rate until expenditure of 300 kcal until the end of training. |
|
| Moderate Intensity Interval Training | Active Comparator | Walking on a treadmill at 60-80% peak heart rate until expenditure of 300 kcal until the end of training. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High Intensity Interval Training | Behavioral | Exercise will be performed at three sessions per week. All sessions will be supervised by a trained health or exercise professional. |
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in endothelial function as measured by flow-mediated vasodilation (FMD) | FMD will be measured using the guidelines reported by Corretti et al. The diameter of the brachial artery will be assessed using a high-resolution ultrasound device (Siemens SG-60, USA), equipped with a 7.5 MHz linear array transducer | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in LDL Cholesterol | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. | |
| Change from Baseline in HDL Cholesterol | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Robinson Ramírez Vélez, Ph.D | Universidad del Rosario | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Robinson Ramírez Vélez Ph.D | Bogotá | Colombia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30717757 | Derived | Ramirez-Velez R, Hernandez-Quinones PA, Tordecilla-Sanders A, Alvarez C, Ramirez-Campillo R, Izquierdo M, Correa-Bautista JE, Garcia-Hermoso A, Garcia RG. Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults. Lipids Health Dis. 2019 Feb 4;18(1):42. doi: 10.1186/s12944-019-0981-z. | |
| 29615070 |
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| ID | Term |
|---|---|
| D008659 | Metabolic Diseases |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D000072696 | High-Intensity Interval Training |
| ID | Term |
|---|---|
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
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| Moderate Intensity Interval Training | Behavioral | Exercise will be performed at three sessions per week. All sessions will be supervised by a trained health or exercise professional. |
|
| Change from Baseline in Triglycerides | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Change from Baseline in Glucose | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Change from Baseline in Heart rate variability | HRV will be performed according to current recommendations by European Society of Cardiology using an evaluated share-ware | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Aortic pulse wave velocity (PWVao) | PWVao (m s-1) will be performed within 3 to 4 minutes with the oscillometric, occlusive device, the Arteriograph. The measurement will be taken in a supine position and were accepted if the quality indicator of the recordings was within the acceptable range (i.e., if the standard deviation [SD] of the beat-to-beat measured PWVao values was less than 1.1 m/sec). | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Change from Baseline in muscular fitness | Muscular fitness (MF) will be assessed using handgrip test (maximum handgrip strength assessment) using a standard adjustable handle analogue handgrip dynamometer T-18 TKK SMEDLY III® | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Change from Baseline in Flexibility using the sit and reach test | It will be determined using a maximum treadmill exercise test (Precor TRM 885, Italy) following the modified Balke protocol | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Change from Baseline in peak uptake of volume of oxygen | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Change from Baseline in Blood Pressure | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Change from Baseline in Body Mass Index | BMI will be calculated as the body weight in kilograms divided by the square of the height in meters. | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Change from Baseline in Body Mass | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Change from Baseline in Quality & satisfaction with life by SF Community - short-form survey (SF-12™) Colombian version | Baseline and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Augmentation index (AIx) | AIx (%) will be performed within 3 to 4 minutes with the oscillometric, occlusive device, the Arteriograph. The measurement will be taken in a supine position and were accepted if the quality indicator of the recordings was within the acceptable range (i.e., if the standard deviation [SD] of the beat-to-beat measured AIx values was less than 1.1 m/sec). | Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal. |
| Ramirez-Velez R, Correa-Rodriguez M, Tordecilla-Sanders A, Aya-Aldana V, Izquierdo M, Correa-Bautista JE, Alvarez C, Garcia-Hermoso A. Exercise and postprandial lipemia: effects on vascular health in inactive adults. Lipids Health Dis. 2018 Apr 3;17(1):69. doi: 10.1186/s12944-018-0719-3. |
| 28558739 | Derived | Ramirez-Velez R, Tordecilla-Sanders A, Tellez-T LA, Camelo-Prieto D, Hernandez-Quinonez PA, Correa-Bautista JE, Garcia-Hermoso A, Ramirez-Campillo R, Izquierdo M. Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults: a randomized clinical trial. J Transl Med. 2017 May 30;15(1):118. doi: 10.1186/s12967-017-1216-6. |
| 28198783 | Derived | Ramirez-Velez R, Tordecilla-Sanders A, Tellez-T LA, Camelo-Prieto D, Hernandez-Quinonez PA, Correa-Bautista JE, Garcia-Hermoso A, Ramirez-Campillo R, Izquierdo M. Effect of Moderate- Versus High-Intensity Interval Exercise Training on Heart Rate Variability Parameters in Inactive Latin-American Adults: A Randomized Clinical Trial. J Strength Cond Res. 2020 Dec;34(12):3403-3415. doi: 10.1519/JSC.0000000000001833. |
| D009142 |
| Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |