Renal Biomarkers to Predict Recovery Following Venoarterial Extracorporeal Membrane Oxygenation

Renal Biomarkers to Predict Recovery Following Venoarterial Extracorporeal Membrane Oxygenation

The investigators objective is to assess the utility of renal biomarkers in predicting renal recovery following institution of Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO). Tissue biomarkers of renal injury may provide a real-time indication of renal function and the likelihood of renal recovery in patients having cardiogenic shock and requiring VA-ECMO. In these patients, traditional markers of kidney function (urine output and serum Creatinine level) do not accurately represent renal function.

Inclusion Criteria:

• age more than 18 years
• refractory or advanced cardiogenic shock prior to institution of VA-ECMO

Exclusion Criteria:

• History of chronic kidney disease prior to cardiogenic shock, as defined by estimated glomerular filtration rate (GFR) less than 60 mL per min
• Cognitive impairment
• Pregnant women
• patient or surrogate is not fluent in English
• Long-term immunosuppression