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| Name | Class |
|---|---|
| Sheba Medical Center | OTHER_GOV |
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The aims of this study are twofold: (1) to develop an innovative approach for studying brain glucose metabolism using functional diffusion weighted imaging (DWI) and BOLD fMRI in humans; (2) to evaluate the effect of short peripheral electrical stimulation (PES) treatment on brain and brain-stem targets, associated with control of food intake and energy expenditure, in response to glucose stimuli, in healthy volunteers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Glucose | Experimental | Glucose ingestion |
|
| PES | Active Comparator | Single session of short PES treatment before glucose ingestion. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Stimulator | Device |
| ||
| Glucose |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in postprandial cerebral blood flow (fMRI) and cerebral diffusivity (fDWI) in response to glucose ingestion. | changes from baseline to 30 minutes after glucose ingestion |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Uri Nevo, PhD | Contact | 972-3-6407542 | nevouri@post.tau.ac.il |
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| ID | Term |
|---|---|
| D014023 | Tissue Therapy, Historical |
| D005947 | Glucose |
| ID | Term |
|---|---|
| D009945 | Organotherapy |
| D001691 | Biological Therapy |
| D013812 | Therapeutics |
| D000529 | Complementary Therapies |
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300ml tap water with 75g glucose |
|
| D006601 |
| Hexoses |
| D009005 | Monosaccharides |
| D000073893 | Sugars |
| D002241 | Carbohydrates |