Retrospective multicentric observational study exploring the population of adult neuromuscular patients presenting a respiratory distress requiring their admission in an Intensive Care Unit (ICU) for ventilatory support.

Research of markers associated with long term mortality and ventilatory status.

Inclusion Criteria:

• Patient > 18 years old
• First stay in a ICU ward
• Inclusion period : Admission in ICU between 01/01/2007 and 31/12/2015
• Presenting an acute respiratory distress at admission or during ICU stay
• Diagnosis of neuromuscular disease confirmed before Hospital discharge

Exclusion Criteria:

• Absence of respiratory failure during ICU stay (ICU stay for monitoring or for a specialized invasive procedure in the absence of respiratory failure, for example)
• Neuromuscular disease not proven or uncertain diagnosis
• Anterior admission in ICU ward for vital organ failure

Adult patients presenting a neuromuscular disease, with involvement of respiratory or bulbar muscles.

Neuromuscular diseases concerned :

Central or Peripheral metabolic, toxic, or inflammatory neuropathies, Central or peripheral neurodegenerative or hereditary disorders Myopathies, amongst them dystrophinopathies, myotonic dystrophies Myasthenia gravis Tetraplegy, consequence of cervical spinal cord injury