Clinical Trail to Evaluate the Efficacy and Safety of Adhesion Barrier Mediclore Versus no Treatment in Patients With Total Thyroidectomy

A Randomized, Single-blind, Multi-center, Phase III Clinical Trail to Evaluate the Efficacy and Safety of Adhesion Barrier Mediclore Versus no Treatment in Patients With Total Thyroidectomy

A randomized, single-blind, multi-center, Phase III clinical trial to evaluate the efficacy and safety of adhesion barrier Mediclore versus no treatment in patients with total thyroidectomy

Inclusion Criteria:

• Written informed consent
• Male or female at least 20 years of age
• Patients without clinically significant lab
• Patients scheduled for thyroidectomy

Exclusion Criteria:

• Another clinical trials within 1 month
• History of previous surgery on same position
• Anticoagulant, general steroids within a week from surgery
• Immunosuppression or autoimmune disease
• General or local infection
• Serious diseases (heart failure, renal failure, liver failure, uncontrolled hypertentsion, diabetes mellitus, coagulation deficiencies)
• Incompatible medications
• History of drug or alcohol abuse, mental disorder
• Pregnant or lactating women and fertile women who is not using proper contraceptive method
• History of esophagus diseases
• Keloid symptoms