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Case-control comparison of clinical population, interventional and single-center research.
The main objective of this study is to define and characterize electrophysiological markers of the existing social cognition disorders in schizophrenia. Two groups of subjects are recorded : schizophrenic patients and healthy controls. Visual reinforcement effect during theory of mind judgment is tested.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients | Experimental | Treated or hospitalized patients for schizophrenia. |
|
| Control | Experimental | No schizophrenic participants, comparable to schizophrenia patients in age, gender, education level and socio premorbid verbal IQ. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Theory of mind without visual cues | Behavioral | Theory of mind stimulation without visual reinforcement while performing EEG recordings |
|
| Measure | Description | Time Frame |
|---|---|---|
| Event related electric amplitudes | Scalp EEG recordings (microvolts) with respect to average or vertex references | Day 0 |
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Inclusion Criteria:
Written informed consent French mother tongue Schizophrenia diagnosis according to DSM-IV-R for the patient group
Exclusion Criteria:
Coma history, epilepsy, head trauma with loss knowledge greater 10 min ECT older than 1 month DSM-4 R criteria of toxic addiction in the last 6 months Deafness or blindness Scalp pathology Intracranial implanted device
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| Name | Affiliation | Role |
|---|---|---|
| Eric Brunet, MD PhD | Versailles Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier de Versailles | Le Chesnay | 78150 | France |
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| ID | Term |
|---|---|
| D012559 | Schizophrenia |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D001523 | Mental Disorders |
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| Theory of mind without visual cues | Behavioral | Theory of mind stimulation with visual reinforcement while performing EEG recordings |
|