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| ID | Type | Description | Link |
|---|---|---|---|
| 2013-A00465-40 | Other Identifier | Ansm |
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High frequency percussive ventilation (HFPV) is a high frequency ventilation mode in which high frequency pulses accumulate to generate a low frequency tidal volume at a controlled airway pressure. Previous studies have suggested a protective effect of HFPV on lung injury. The goal of our study is to compare, in early ARDS patients, the effects of conventional mechanical ventilation and of high frequency percussive ventilation on alveolar recruitment and distension evaluated by CT-scan
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Transpulmonary pressure controlled mechanical ventilation | Experimental | transpulmonary pressure will be used for ventilation settings |
|
| Conventional pressure-controlled mechanical ventilation | No Intervention | transpulmonary pressure will not be used for ventilation settings |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High frequency percussive ventilation | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| Percent of patients exhibiting under HFPV an increase of at least 15% of normally aerated end-expiratory lung volume | 4 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Urielle DESALBRES | Assistance Publique-Hôpitaux de Marseille | Study Director |
| Antoine ROCH, MD/PhD | Assistance Publique-Hôpitaux de Marseille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assistance Publique-Hôpitaux de Marseille | Marseille | 13354 | France |
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