Evaluation of the Sensitivity of a Transdermal Device to Monitor the Sweat Alcohol Concentration

Evaluation of the Sensitivity of a Transdermal Device to Monitor the Sweat Alcohol Concentration

A non invasive transdermal sensor device was developed by the Im2Np laboratory to determine the presence of vapor of alcohol in insensible perspiration.

One of possible application would be a continuous and non invasive monitoring of drinking behavior. To investigate the validity of this method, it's necessary to compare Transdermal Alcohol Concentrations results obtained by this new device with Blood Alcohol Concentrations and breath Alcohol Concentrations provided by reference methods.

The purpose of this study is to identify the kinetic of alcohol concentration in blood, exhaled air and sweat after alcohol ingestion.

Inclusion Criteria:

• Male or female 18-40 years, age-matched (+ 3 years)
• Caucasian
• BMI: 19 to 28 kg/m2
• No smoking or light smoker (<5 cig/d)
• Moderate consumer of alcohol (3-14 drinks/week), with the intoxicated experience

Exclusion Criteria:

• Subjects with addiction to toxic or alcohol (MINI Questionnaire)
• Positive individuals in search of drugs and toxic
• Anxiety or depressive subjects (IASTA Questionnaires and BDI)