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Examination if the bioimpendanz measurement can be used for the determination of the alcohol content in human blood.
Furthermore the blood alcohol content (BAC) will be estimated by an official breathalyzer and one blood test.
In this clinical trail it will be analyzed, if it is possible to assess the blood alcohol content (BAC) with the bioimpedance devices (SFB7, ImpediMed; Nicomo).
This technology is non-invasive an can be measured by using conductive electrodes, capacitive electrodes or inductive measurement systems.
The BIS-values will be compared with an official breathanalyzer (Alcotest 7110 Evidential MK III, Dräger, Lübeck, Germany).
Furthermore one blood sample will be taken and analyzed with the ADH method as the current gold standard at the end of the trail.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| bioimpedance measurements while trinking alcohol | Bioimpedance spectroscopy (BIS) measurements on 12 healthy subjects were performed while they were drinking alkohol until reaching a BAC of 0.8 ‰. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| bioimpedance mesurements | Device | Bioimpedance measurements were conducted with a BIS device (SFB7, ImpediMed, Pinkeba, Australia) covering a frequency range between 5 kHz and 1 MHz and an ICG device (Niccomo, medis, Ilmenau, Germany) |
| Measure | Description | Time Frame |
|---|---|---|
| Bioimpedance measurements | Evaluation if the bioimpedance measurements can be used to verify and quantify the alcohol content in human blood. Bioimpedance measurements will be conducted with the BIS device (SFB7, ImpediMed) covering a frequency range between 5 kHz and 1 MHz and an ICG device (Niccomo,medis) operating at. The whole-body and hand-to-hand bioimpedance will be analyzed. Extracellular resistance (Re), intracellular resistance (Ri) and capacitive effects (Cm) are calculated by using the Cole model Grimnes (2000). | 4 hours |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy male subjects
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| Name | Affiliation | Role |
|---|---|---|
| Michael Czaplik, Dr. med. | Department of Anaesthesiology ,Chair for Medical Information Technology Helmholtz Institute for Biomedical Engineering RWTH Aachen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Anaesthesiology, University Hospital Aachen | Aachen | North Rhine-Westphalia | 52074 | Germany |
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