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This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay and incidence of chronic pain,et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic renal surgeries.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| single-injection QLB(quadratus lumborum block) | Experimental | Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia) |
|
| IPCA | Active Comparator | postoperative IPCA is given alone |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| single-injection QLB(quadratus lumborum block) | Procedure | Inject local anesthetics in between quadratus lumborum and psoas major without continuous local infusion |
|
| Measure | Description | Time Frame |
|---|---|---|
| cumulative morphine consumption | within 48 postoperative hours |
| Measure | Description | Time Frame |
|---|---|---|
| The pain scores determined by the numeric rating scale (NRS, 0-10) | At 0, 2,4, 8, 12, 24 ,48,72hours after the surgery | |
| nausea and vomiting score | within 24 hours after the surgery | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yuguang Huang, MD. | Peking Union Medical College Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xulei CUI | Beijing | Beijing Municipality | 100730 | China |
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| Philip CX50 Ultrasound Scanner | Device | The curved (C1-5) probe of Philip CX 50 Ultrasound Scanner is used for scan |
|
| PAJUNK StimuLong | Device |
|
| single dose ropivacaine | Drug |
|
|
| Morphine given as IPCA(intravenous patient controlled analgesia) | Drug | bolus: 1.5~2mg, lock time: 10min, 1h limitation: 6~8mg |
|
| pruritus score |
| within 24hour after the surgery |
| ambulation time | within the 7 days after surgery |
| time of recovery of bowl movement | within the 5 days after surgery |
| quality of recovery | use the self-assessment 15 item QoR scale to assess the patient's recovery | 3days and 5days after surgery |
| Postoperative hospital length of stay | Up to 6 weeks |
| patient satisfaction with anesthesia | use the Chinese version Bauer questionnaire to assess the patient satisfaction with anesthesia | 48 hours after surgery |
| ID | Term |
|---|---|
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D000077212 | Ropivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |
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