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This prospective, randomized control study aims to compare the analgesic effect, satisfaction with anesthesia and analgesia between single-injection QLB (quadratus lumborum block)+general anesthesia (GA) and general anesthesia (GA) alone in patients undergoing laparoscopic adrenalectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| single-injection QLB (quadratus lumborum block) | Experimental | Single-injection of QLB with local anesthetic is given preoperatively |
|
| Placebo control | Placebo Comparator | Single-injection of QLB with NS is given preoperatively |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| single-injection QLB(quadratus lumborum block) | Procedure | Inject 0.4ml/kg 0.5% ropivacaine between quadratus lumborum and psoas major muscle Device: The curved (C1-5) probe of Ultrasound Scanner Philips CX50 is used for scan Drug: single dose ropivacaine 0.4ml/kg 0.5% ropivacaine is given immediately after the correct position of needle tip is verified. |
| Measure | Description | Time Frame |
|---|---|---|
| the NRS pain scores on activity 12-hours after surgery | The NRS (a number scale from 0 to 10) is a commonly used pain intensity rating tool | 12-hours after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| the pain scores at rest determined by the numeric rating scale (NRS, 0-10) | The NRS (a number scale from 0 to 10) is a commonly used pain intensity rating tool | At 2,4, 8, 12, 24 ,48,72 hours after the surgery |
| incidence of postoperative nausea and vomiting (PONV) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yuguang Huang | PUMCH | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking Union Medical College Hospital | Beijing | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34753425 | Derived | Yuan Q, Lu S, Cui X, Zhang Y, Xie Y, Zhang Y, Yan W, Ji Z, Huang Y. Transmuscular quadratus lumborum block for postoperative pain and recovery after laparoscopic adrenalectomy: a randomized controlled trial. BMC Anesthesiol. 2021 Nov 9;21(1):274. doi: 10.1186/s12871-021-01494-4. |
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| ID | Term |
|---|---|
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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|
| Placebo Control | Procedure | Inject 0.4ml/kg saline between quadratus lumborum and psoas major muscle Device: The curved (C1-5) probe of Ultrasound Scanner Philips CX50 is used for scan Drug: single dose 0.4ml/kg 0.9% NS is given immediately after the correct position of the needle tip is verified |
|
| within 24 postoperative hours |
| ambulation time | within 5 days after surgery |
| time of recovery of bowel movement | defined as the time to first flatus | within 5 days after surgery |
| postoperative length of hospital stay | up to 2 weeks after surgery |
| patient's satisfaction of anesthesia and analgesia | use the Chinese version of Bauer questionnaire to assess the patient satisfaction of anesthesia | 48 hours after surgery |
| the NRS pain scores on activity after surgery | The NRS (a number scale from 0 to 10) is a commonly used pain intensity rating tool | At 2,4, 8, 24 ,48,72 hours after the surgery |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |