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The primary purpose of this study is to investigate the effect of intravenous magnesium on postoperative throat pain after thyroidectomy.
The secondary purpose of this study is to investigate the effect of intravenous magnesium on total dose of fentanyl in recovery room after thyroidectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Magnesium group | Experimental | intravenous administration of Magnesium Sulfate |
|
| Control group | Placebo Comparator | intravenous administration of normal saline |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Magnesium Sulfate | Drug | adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h |
|
| Measure | Description | Time Frame |
|---|---|---|
| Throat pain | pain assessment using visual analog scale | Up to 48 hours after surgery end |
| Measure | Description | Time Frame |
|---|---|---|
| Fentanyl dose in recovery room | Up to 30 minutes after surgery end |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine | Suwon | Seoum | South Korea |
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| ID | Term |
|---|---|
| D013964 | Thyroid Neoplasms |
| ID | Term |
|---|---|
| D004701 | Endocrine Gland Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D006258 | Head and Neck Neoplasms |
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| ID | Term |
|---|---|
| D008278 | Magnesium Sulfate |
| D000077330 | Saline Solution |
| ID | Term |
|---|---|
| D017616 | Magnesium Compounds |
| D007287 | Inorganic Chemicals |
| D013431 | Sulfates |
| D013464 | Sulfuric Acids |
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| Normal saline | Drug | the same bolus and infusion volumes of normal saline |
|
| D004700 |
| Endocrine System Diseases |
| D013959 | Thyroid Diseases |
| D013456 |
| Sulfur Acids |
| D013457 | Sulfur Compounds |
| D000077324 | Crystalloid Solutions |
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |