Comparison of the Effect of Magnesium Sulfate and Dexamethasone on Postoperative Sore Throat After Spinal Surgery in Prone Position With Tracheal... | NCT01923831 | Trialant
CompletedInterventionalNot ApplicableUpdated Mar 17, 2015
Comparison of the Effect of Magnesium Sulfate and Dexamethasone on Postoperative Sore Throat After Spinal Surgery in Prone Position With Tracheal Intubation: a Double-blind, Randomized, Noninferiority Clinical Trial
ClinicalTrials.gov ID
NCT01923831
Lead Sponsor
Yonsei UniversityOTHER
Overall Status
Completed
Study Type
Interventional
Phase
Not Applicable
Enrollment
146Actual
Last Update Posted
Mar 17, 2015Estimated
Start Date
Aug 2013
Primary Completion Date
Sep 2014Actual
Completion Date
Sep 2014Actual
Brief Summary
The purpose of this study is to compare the effect of magnesium sulfate and dexamethasone on postoperative sore throat after spinal surgery in prone position with tracheal intubation.
Post Operative Sore Throat
Magnesium Sulfate
dexamethasone
Ages Eligible for Study
Adult (18-64)Older Adult (65+)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
ASA I-II patients aged between 20 and 65 year undergoing 1 or 2 level posterior spinal fusion in prone position with tracheal intubation
Exclusion Criteria:
preexisting hoarseness or sore throat, upper respiratory tract infection
steroid therapy or immunocompromised patients
chronic treatment with calcium channel blocker or magnesium
allergy to magnesium sulphate
Cormack-Lehane grade 3,4 or patients who are expected to difficult intubation
fail to tracheal intubation at first trial
reduced kidney function
Diabetes mellitus
Primary Purpose
Prevention
Allocation
Randomized
Interventional Model
Parallel Assignment
Masking
Triple
No central contacts
There are no central contacts for this study.
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine