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The ketone body beta-hydroxybutyrate is produced during prolonged fasting or exercise and can be used as an alternative fuel source. Exogenous beta-hydroxybutyrate, in the form of a ketone salt, is proposed to have ergogenic potential for high-intensity exercise performance but this has not been adequately studied. The purpose of this study is to determine whether supplementing with an acute dose of ketone salts can alter fuel use during exercise and improve exercise performance.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ketone Salts | Experimental | Acute dose of beta-hydroxybutyrate potassium/sodium salt (0.2g beta-hydroxybutyrate/kg, 0.01g Potassium/kg, 0.01g Sodium/kg with 1 g Steviol Glycoside and 30 ml of lemon juice per dose) |
|
| Placebo | Placebo Comparator | Acute dose of taste-matched placebo (0.01g Potassium/kg, 0.01g Sodium/kg with 1 g Steviol Glycoside and 30 ml of lemon juice per dose) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ketone Salt | Dietary Supplement |
| ||
| Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| Respiratory Exchange Ratio (RER) during cycling exercise | The RER during 18 minutes of steady-state exercise | 0-18 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| 10 km Cycling Time Trial Performance | 10 km time trial performed on a stationary bicycle following 18 minutes of steady-state exercise | Following 18 minutes of steady-state exercise |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of British Columbia, Okanagan. | Kelowna | British Columbia | V1V 1V7 | Canada |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D007662 | Ketosis |
| ID | Term |
|---|---|
| D001519 | Behavior |
| D000138 | Acidosis |
| D000137 | Acid-Base Imbalance |
| D008659 | Metabolic Diseases |
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|
| D009750 |
| Nutritional and Metabolic Diseases |