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Retrospective study to evaluate the impact of computational wall stress analysis based on computed tomography (CT) of ruptured and not-ruptured aortic aneurysms as an additional predictor for rupture with dedicated software.
In patients with known aortic aneurysm who received clinically indicated CT during a time period from 01/2004-12/2013 the CT data was evaluated with dedicated software, A4clinics, VASCOPS GmbH, Graz, Austria. The following parameters will be evaluated: exterior and luminal diameter, intraluminal thrombus (ILT) thickness, vessel-, luminal- and intraluminal thrombus volume, peak wall stress (PWS), peak wall rupture risk (PWRR), von Mises-stress and rupture risk-index in the ILT.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| asymptomatic not ruptured aneurysm | Patients with asymptomatic not ruptured aortic aneurysms greater than 3 cm who received a clinical indicated CT |
| |
| symptomatic not ruptured aneurysm | Patients with symptomatic aortic aneurysms greater than 3 cm who received a clinical indicated CT |
| |
| symptomatic ruptured aneurysm | Patients with symptomatic ruptured aortic aneurysms greater than 3 cm who received a clinical indicated CT |
| |
| patients with small aneurysms | Patients with small aortic aneurysms approximately 5.5 cm, ruptured and not ruptured, who received a clinical indicated CT |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CT-acquisition | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| To calculated the rupture risk equivalent diameter (RRED) of the aortic aneurysm and rupture risk-index in the intraluminal thrombus within the aortic aneurysm. | By using the finite analysis from the CT data the peak wall stress (PWS), the peak wall rupture (PWRR) and the mises stress within the aortic aneurysm depending on the diameter and volume of the aortic aneurysm and of the intraluminal thrombus will be measured. | CT Data from 01/2004-12/2013 |
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Inclusion Criteria:
Clinical indicated CT data from patients with known aortic aneurysms.
Clinical indication was:
Exclusion Criteria:
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Patients with known aortic aneurysms, who underwent clinical indicated CT during a time period from 01/2004-12/2013
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Zurich | Recruiting | Zurich | Canton of Zurich | 8091 | Switzerland |
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| ID | Term |
|---|---|
| D001014 | Aortic Aneurysm |
| ID | Term |
|---|---|
| D000783 | Aneurysm |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D001018 | Aortic Diseases |
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