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| ID | Type | Description | Link |
|---|---|---|---|
| 2A3360 | |||
| FAMRI 2 |
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| Name | Class |
|---|---|
| Flight Attendant Medical Research Institute | OTHER |
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Can software be developed to automatically aid in the measurement of abdominal aortic aneurysms, and is there a way to predict future rupture or growth of abdominal aortic aneurysms.
Hypothesis: ECG-gated multidetector CT and ECG-gated Dual Source CT can be used to create multiple volumetric datasets of the abdominal aorta over the time period of the cardiac cycle, allowing for direct and regional calculations of abdominal aortic distensibility over the entire volume of the abdominal aorta, providing insight into risk of abdominal aortic aneurysm rupture and early large vessel stiffness.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Aortic aneurysm repair | ||
| 2 | Aortic aneurysm growth | ||
| 3 | Aortic aneurysm growth stable. |
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| Measure | Description | Time Frame |
|---|---|---|
| In year one, this data will be used to develop pulsatility software and test robustness. | First Year |
| Measure | Description | Time Frame |
|---|---|---|
| In year two, the time-resolved CT angiographic datasets from each patient will be analyzed to determine peak AAA pulsatility and peak AAA relative pulsatility (to cross-sectional area within the aneurysm). | Year Two |
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Inclusion Criteria:
Exclusion Criteria:
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Patients undergoing imaging of their abdominal aortic aneurysm
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| Name | Affiliation | Role |
|---|---|---|
| Joel G. Fletcher, M.D. | Mayo Clinic - Rochester, Minnesota | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mayo Clinic | Rochester | Minnesota | 55905 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 17885194 | Background | Zhang J, Fletcher JG, Vrtiska TJ, Manduca A, Thompson JL, Raghavan ML, Wentz RJ, McCollough CH. Large-vessel distensibility measurement with electrocardiographically gated multidetector CT: phantom study and initial experience. Radiology. 2007 Oct;245(1):258-66. doi: 10.1148/radiol.2451060530. | |
| Background | Wentz RJ, Manduca A, Fletcher JG, Siddiki HA, Shields RC, Vrtiska TJ, Spencer GC, Primak AN, Zhang J, Nielson TA, McCollough CH, Yu L. SPIE Medical Imaging 2007.: Physiology, Function, and Structure from Medical Images, 2007; 6511:1-9 |
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| ID | Term |
|---|---|
| D017544 | Aortic Aneurysm, Abdominal |
| ID | Term |
|---|---|
| D001014 | Aortic Aneurysm |
| D000783 | Aneurysm |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| D001018 |
| Aortic Diseases |