Dexamethasone Added in Ultrasound-guided Transversus Abdominis Plain Block for Postoperative Analgesia

Dexamethasone Added to Levobupivacaine in Ultrasound-guided Tranversus Abdominis Plain Block Increased the Duration of Postoperative Analgesia After Laparoscopic Cholecystectomy

Dexamethasone Added to Levobupivacaine in Ultrasound-guided Tranversus Abdominis Plain Block Increased the Duration of Postoperative Analgesia After Laparoscopic Cholecystectomy.

In the ultrasound-guided TAP-Block with Dexamethasone group, dexamethasone is added to Levobupivacaine in Ultrasound-guided Tranversus Abdominis Plain Block after Laparoscopic Cholecystectomy. In the ultrasound-guided TAP-Block with saline group, saline is added to Levobupivacaine in Ultrasound-guided Tranversus Abdominis Plain Block , after Laparoscopic Cholecystectomy. In the ultrasound-guided TAP-Block with intravenously dexamethasone group, dexamethasone is intravenously injected , after Laparoscopic Cholecystectomy. After surgery the extension of postoperative analgesia, incident and rest pain were evaluate in each group.

Inclusion Criteria:

• Patients with ASA score I and II
• age 18 years

Exclusion Criteria:

• Allergy to local anesthetics
• Allergy to general anesthetics
• Allergy or intolerance to acetaminophen
• Severe renal impairment
• Severe hepatic impairment
• Congestive heart failure
• Coagulation disorders
• hypoprotidemia
• Diabetes mellitus History
• Age greater than 70 years
• Age below 18 years
• ASA Physical than 3 Status
• Lack of informed consent
• Patients unable to discernment
• Intolerance to opiates
• Peptic Ulcer
• Abuse of alcohol and / or drugs