To evaluate the safety and efficacy of Restylane Silk for photoaged thinned hands

Inclusion Criteria:

• Female volunteer
• Aged from 40-70 years on the day of screening
• No known medical conditions that may interfere with study participation
• Moderate to very severe Photoaged thinning of the hands based on the 5-point hand grading scale
• Willingness to not use any products on their hands for the duration of the study
• Read, understand, and sign informed consent forms
• Willingness to sign photography release form
• Willing and able to comply with all follow-up requirements
• Willingness to undergo Restylane Silk injections to one hand

Exclusion Criteria:

• Any significant skin disease at treatment area
• Any medical condition which could interfere with the treatment
• Inability or unwillingness to follow the treatment schedule
• Inability or unwillingness to sign the informed consent
• History of poor wound healing
• History of keloid formation
• History of HIV, hepatitis, immuno-compromised
• Pregnant or lactating
• Previous use of deep chemical peels on the treatment area
• Previous injections of Restylane Silk to the hands
• Known hypersensitivity to Restylane Silk or any of its ingredients
• Previous laser or light based treatments to the treatment area 6 months prior to the screening visit