The purpose of this study is to determine the safety and efficacy of using Restylane Vital for skin rejuvenation of the dorsal hands. Assessment of improvement of skin structure will be done by a blinded evaluator.

Inclusion Criteria:

• Signed Informed Consent
• Chinese origin
• Subject willing and able to comply with the requirements of the study and agrees to adhere to the visit schedule and to be compliant to the study instructions

Exclusion Criteria:

• Any previous non-permanent implant/filler in the hands
• Any mesotherapy or resurfacing procedure in the hands within 6 months prior to baseline
• Any previous hand surgery
• Any fibrosis or scarring or deformities on the hands
• Advanced photoaged/photodamaged skin

1 year, 6 months (AE reporting on each subject started at visit 2 and continued during each follow-up visit (including telephone contacts and extra visits between planned visits) until the last scheduled visit in the study.)

Each subject should be questioned about AEs at each study visit following the screening visit.

The question asked should be:"Since your last clinical visit have you had any health problems?" Information on AEs can also be obtained from signs and symptoms detected during each examination, observations made by the study site personnel, subject diaries, or spontaneous reports from the subjects.