Vestibular stimulation has been shown to be a very effective noninvasive treatment for major depression. Bipolar disorder is a mental illness that presents cyclic sequences of depressive and euphoric states. Depressive phases of bipolar disorder are difficult to treat and usually are resistant to actual available treatments. This study investigates the effectiveness of a particular technique of vestibular stimulation in a group of 120 bipolar type I and II patients. After randomization 60 of them will receive specific vestibular stimulation (experimental group) and 60 will receive a sham vestibular stimulation.The study will conducted in Vest Brain, Centro de Estudios Neurovestibulares, in Chile.

Inclusion Criteria:

• males
• females
• 3 previous weeks with depression symptoms.
• bipolar disorder type I actual depressive phase
• bipolar disorder type II actual depressive phase
• Montgomery Asberg depression scale(MADRS) score equal or more than 20
• stable psychiatric medication during 2 weeks previous the recruitment

Exclusion Criteria:

• pregnancy
• neurologic disorder
• drugs or alcohol abuse during the 2 weeks previous the recruitment
• presence of maniac state(Young mania scale score more than 7)

IPD will be shared with other researchers by asking for the information to Dr. Ana María Soza's email: amsozaried@vestbrain.cl

The data will be available in December 2019-March 2020 and can be asked to Dr. Ana María Soza´s email amsozaried@vestbrain.cl

The criteria to access is asking for the information to Dr. Ana María Soza´s email amsozaried@vestbrain.cl