Study of a Vestibular Biomarker of Phase in Bipolar Disorder

Exploratory Study of a Vestibular Biomarker of Phase in Bipolar Disorder

Bipolar Disorder show cyclic changes of mood between depression (depressive phase) and mania (maniac phase). Vestibular tests have been shown high sensibility and specificity as a biological marker for major depression. This exploratory investigation will measure and compare the vestibular activity of bipolar disorder patients during different phases ( 6 depressed phase, 6 maniac phase, 6 euthimic and 6 control healthy subjects).

Inclusion Criteria:

• Bipolar disorder I or II
• depressive phase of bipolar disorder
• maniac phase of bipolar disorder
• euthimic phase of bipolar disorder

Exclusion Criteria:

• drugs addiction
• alcohol addiction
• neurologic condition, disorder