Assessment of the Impact of Probiotics on Biofilm Formation on Removable Acrylic Dentures

Assessment of the Impact of Probiotics on Biofilm Formation on Removable Acrylic Dentures

The aim of this study is to evaluate the effect of PIP toothbrush cleaner® on the microbial composition and Candida albicans colonization of denture biofilm formation. Additionally, its effect will be compared to that of cleansing tablets.

Therefore the present study intended to compare a probiotic denture cleaning protocol with the current protocols. It was aimed to examine, in institutionalized older individuals with removable complete dentures, if the microbial composition and C. albicans colonization of the denture biofilm differs when overnight stored in a probiotic cleaning product compared to water or a cleanser. Additionally the influence of brushing on these protocols was investigated.

Inclusion Criteria:

• Reside in a home for elderly
• Fully edentulous in lower and upper jaw
• Removable denture wearer in lower and upper jaw
• Good oral health

Exclusion Criteria:

• Current or history of corticosteroid treatment within the 3 months prior to the study
• Current or history of antimicrobial treatment within the 3 months prior to the study
• Inability to provide informed consent
• Inability to comply with the study requirements
• Heart disorders persons with a high risk for an unfavourable prognosis of bacterial endocarditis will be excluded. This applies to patients with prosthetic heart valves, history of infectious endocarditis, cyanogenic congenital heart disorders (including palliative shunts and connections), completely recovered congenital disorders that were treated less than 6 months ago, treated congenital heart disorders with residual defect, and valvulopathy after heart transplantation.