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To measure the absorption kinetics and postprandial amino acid availability after ingestion of minced beef compared with hydrolyzed beef in young males. Moreover, the basal muscle protein synthesis and the postprandial muscle protein synthetic response to minced beef and hydrolyzed beef ingestion are measured in young males. The postprandial muscle protein synthetic response is measured and compared during the early postprandial period (0-3 hours) after ingestion of the two meat products.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Minced beef | Active Comparator | Minced beef |
|
| Hydrolyzed beef | Experimental | Hydrolyzed beef |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Minced beef | Dietary Supplement | Cow meat protein supplement |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change in skeletal muscle protein fractional synthetic rate | The fractional synthetic rate of skeletal muscle proteins (%/h) measured during the overnight fasted state and the postprandial state. | During the postprandial period (0-3 hrs). |
| Measure | Description | Time Frame |
|---|---|---|
| Protein absorption | The change in venous plasma ring-2H5-phenylalanine enrichment after ingestion of meat protein, reflects the protein absorption from the meat protein products. | During the postprandial period (0-3 hrs). |
| Plasma amino acid concentration |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kasper Dideriksen, PhD | Contact | +45 35313948 | kasperjuel@hotmail.com | |
| Lars Holm, PhD | Contact | larsh@sund.ku.dk |
| Name | Affiliation | Role |
|---|---|---|
| Kasper Dideriksen, PhD | Bispebjerg Hospital | Principal Investigator |
| Lars Holm, PhD | Bispebjerg Hospital | Principal Investigator |
| Søren Reitelseder, PhD |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bispebjerg Hospital | Copenhagen NV | 2400 | Denmark |
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| Hydrolyzed beef |
| Dietary Supplement |
Cow meat protein supplement |
|
Change in venous plasma amino acid concentration after ingestion of meat protein. |
| During the postprandial period (0-3 hrs). |
| Bispebjerg Hospital |
| Principal Investigator |