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The goal of the study is to determine whether there are age-, diet- and genetically-related differences in the perception of sweeteners, both nutritive and non-nutritive.
This is an observational 3-day study of children between the ages of 7 and 14 and their mothers. A variety of psychophysical methods determined liking for each of the sweeteners and saliva samples were obtained for genotyping of taste receptor genes. Anthropometric and dietary intake measures were also collected.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Age Group-Children | Children between ages of 7 and 14 |
| |
| Age Group-Adults | Healthy adults who are the parent of the children |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| sweeteners | Other | Participants tasted a variety of nutritive and nonnutritive sweeteners |
|
| Measure | Description | Time Frame |
|---|---|---|
| Liking for the taste of sweeteners measured via the 3-point facial hedonic scale. | Through study completion, an average of 6 months. | |
| Liking for the taste of sweeteners measured via the 5-point facial hedonic scale | Through study completion, an average of 6 months. | |
| Liking for the taste of sweeteners measured via the Monell forced-choice, paired-comparison tracking procedure. | Through study completion, an average of 6 months. |
| Measure | Description | Time Frame |
|---|---|---|
| Genotyping of taste receptor genes via saliva donation | Genotyping will be completed to measure associations between individual taste receptor genotypes and liking of sweeteners. | Through study completion, an average of 6 months |
| BMI calculated from body weight and height measures |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy children and adults living in the Philadelphia area
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| Name | Affiliation | Role |
|---|---|---|
| Julie A Mennella, PhD | Monell Chemical Senses Center | Principal Investigator |
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| ID | Term |
|---|---|
| D013549 | Sweetening Agents |
| ID | Term |
|---|---|
| D005421 | Flavoring Agents |
| D005503 | Food Additives |
| D000074385 | Food Ingredients |
| D020313 | Specialty Uses of Chemicals |
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Salivary samples obtained for genotyping of taste receptor genes
BMI will be calculated to examine associations between this measure and liking for sweeteners. |
| Through study completion, an average of 6 months |
| One day dietary intake collected via the Automated Self-Administered 24-hour dietary recall (ASA24). | Dietary recall will be completed to examine associations between added sugar intake and liking for sweeteners. | Through study completion, an average of 6 months |
| D020164 |
| Chemical Actions and Uses |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |