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Aim:
To evaluate effect of non- surgical periodontal therapy on liver function in systemically healthy chronic periodontitis (CP) subjects.
Materials and methods:
The study is non surgical interventional trial, includes 50 CP subjects in the age group of 35- 60 years selected from the OPD (Out Patient Department) of department of periodontology Tatyasaheb Kore Dental College and Research center (TKDC and RC), Kolhapur. CP subjects were equally divided into test group and control group. Liver function test- aspartate aminotransferase (AST), alanine aminotransferase (ALT) were checked at baseline and at 1 month after treatment. Clinical examination includes plaque index, gingival index, sulcus bleeding index, probing depth, clinical attachment loss.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Scaling and Root Planing( SRP) | Active Comparator | This was an interventional study in which scaling and root planing was done in systemically healthy patients with chronic periodontitis |
|
| Control Group | No Intervention | Scaling and root planing was not done , that is no intervention is carried out in the patients of this group. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Scaling and root planing | Procedure | scaling and root planing as an intervention was done in patients of the test group |
|
| Measure | Description | Time Frame |
|---|---|---|
| Alanine aminotransferase | 1month | |
| Aspartate aminotransferase | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| plaque index | 1month | |
| gingival index | 1 month | |
| sulcus bleeding index |
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Inclusion Criteria:
Subjects with CP (moderate and severe) as per Centers for disease control and prevention (CDC) criteria 2007.
Patients without any known systemic diseases
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Exclusion Criteria:
Patients who have taken anti-inflammatory/antibiotic/antioxidant within 3 months of beginning of study.
Subjects who have undergone periodontal treatment within six months of inception of study.
Smokers, tobacco habits in any form and alcoholics.
Pregnant and lactating women.
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| 1month |
| probing depth | 1month |
| Clinical attachment loss | 1 month |
| ID | Term |
|---|---|
| D055113 | Chronic Periodontitis |
| ID | Term |
|---|---|
| D010518 | Periodontitis |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D014080 | Tooth Exfoliation |
| D016745 | Root Planing |
| ID | Term |
|---|---|
| D009063 | Dental Physiological Phenomena |
| D055688 | Digestive System and Oral Physiological Phenomena |
| D012534 | Dental Scaling |
| D003777 | Dental Prophylaxis |
| D010517 | Periodontics |
| D003813 | Dentistry |
| D013357 | Subgingival Curettage |
| D011313 | Preventive Dentistry |
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