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The objective of this study was to evaluate intubating condition using the McGrath® VL Series 5, with and without muscle relaxant
Thirty-four patients with ASA classification I-II, who required oroendotracheal tube intubation, were studied in this prospective, double-blinded, randomized, clinical trial. Anesthesia was induced using fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg. Patients were randomly assigned to one of the two groups to receive either rocuronium 0.6 mg/kg or saline intravenously. The Mcgrath® VL intubation was initiated after 90s, when the patients were fully relaxed. The primary outcome was to compare tracheal intubating conditions between two groups. The secondary outcomes were the success rate in the first attempt intubation, time to intubation, the required propofol dose for intubation and anesthetic complications. Statistical analyses were performed using the R program version 2.14.2. The level of statistical significance was set at p < 0.05.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Muscle relaxant | Experimental | Intubation with McGrath video laryngoscope after fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg muscle relaxant use rocuronium 0.6 mg/kg |
|
| Placebo | Placebo Comparator | Intubation with McGrath video laryngoscope after fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg placebo use NSS 0.6 mg/kg |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Videolaryngoscope | Device | Intubation with McGrath video laryngoscope after muscle relaxant |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intubating condition. | number of participants with 34 people | one year |
| Measure | Description | Time Frame |
|---|---|---|
| Success rate in the first attempt intubation. | one year | |
| Time to intubation | One year | |
| The required propofol dose for intubation without muscle relaxant. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Piyaporn Vasinanukorn, MD. | Prince of Songklanagarind University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of anesthesiology | Hat Yai | Changwat Songkhla | 90110 | Thailand |
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| ID | Term |
|---|---|
| D009123 | Muscle Hypotonia |
| ID | Term |
|---|---|
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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| one year |
| Events during the intubation attempts occurred. | one year |
| D013568 | Pathological Conditions, Signs and Symptoms |