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| Name | Class |
|---|---|
| PepsiCo Global R&D | INDUSTRY |
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A diet rich in whole grain is inversely associated with cardiovascular disease risk and this benefit could be partly attributed to the phenolic acid content of whole grains. The exact absorption, metabolism and excretion of whole grain phenolic acids, however, is not fully understood. In a small human intervention trial, the investigators will investigate to what extent phenolic acids from whole grain oats are absorbed, excreted in urine and how they are metabolised.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oat bran | Experimental | 66g oat bran made up in 350ml skimmed milk |
|
| Control | Placebo Comparator | Refined grain product and 350ml skimmed milk |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oat bran | Dietary Supplement | 66g oat bran made up in 350ml skimmed milk |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in phenolic acid metabolite excretion | Baseline and 48 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Food and Nutritional Sciences | Reading | Berkshire | RG6 6AP | United Kingdom |
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| ID | Term |
|---|---|
| D015799 | Gyrate Atrophy |
| ID | Term |
|---|---|
| D015785 | Eye Diseases, Hereditary |
| D005128 | Eye Diseases |
| D015862 | Choroid Diseases |
| D014603 | Uveal Diseases |
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| refined grain |
| Dietary Supplement |
refined grain product and 350ml skimmed milk |
|
| D030342 |
| Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |