A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients

A Comparative Study of Azithromycin and Sulphadoxine-pyrimethamine as Prophylaxis Against Malaria in Pregnant HIV Positive Patients

Randomized controlled single blind prospective comparative study

This study is intended to be a randomized controlled single blind prospective comparative study conducted to compare the efficacy of three monthly doses of sulphadoxine-pyrimethamine as intermittent preventive therapy for malaria with azithromycin in HIV positive pregnant women

Inclusion Criteria:

• Pregnant HIV positive patients,
• Gestational age 16 weeks and above,
• No history of azithromycin or sulphadoxine-pyrimethamine use four weeks prior to recruitment

Exclusion Criteria:

• Anaemia packed cell volume less than 30%,
• pre-existing medical conditions- diabetes mellitus,
• hypertension,
• allergy to sulphadoxine-pyrimethamine or azithromycin