Development of Rational Ways of Medical and Non-medical Treatment Methods for Metabolic Syndrome

Phase 1-2 Study of Development of Rational Ways of Medical and Non-medical Treatment Methods for Metabolic Syndrome

Metabolic syndrome: aetiology, pathogenesis, diagnosis, clinical management and prognosis

Purpose: To create the complex scientifically proved concept of Metabolic syndrome (МS) development based on elaboration of the new methods of clinical diagnostics of МS components and highly effective МS clinical management in comparative studying of clinical, laboratory and cost effectiveness.

Participants and methods: This clinical study included 351 adults (184 female) in the Scientific research institute of cardiology and internal diseases (Almaty, the Republic of Kazakhstan). Statistical analysis was performed using Microsoft Excel-2008 in updating Lapach, Chubenko et al (2000) and SPSS for Windows v.17.0.

Inclusion Criteria:

• written consent form
• age> 25 years
• skinfold thickness > 0,7 cm BP> 130/85 mm Hg or a patient on antihypertensive medications fasting blood glucose > 6.1 mmole/L, or 2-hour postprandial glucose level > 11.1 mmole/L / or a patient with type 2 diabetes blood cholesterol > 5.6 mmole/L possibility of treatment > 6 months follow-up > 1 year

Exclusion Criteria:

• complete immobilization of a patient (paresis /paralysis)
• patients with severe concomitant diseases of the kidneys and (or) of the liver
• early post-operative condition
• mental illness
• pregnancy
• persons who are in prison
• persons who are in military Armed Forces