Physical and Chemical Study of Atherosclerosis Mechanisms

Comparative Physical and Chemical Study of the Mechanisms of Atherosclerosis With Development of Concept of Treatment and Prevention

Study the mechanisms of atherosclerosis based on a comparative study of physical and chemical properties of lipid tissues at various localization with subsequent development of concept of treatment and prevention.

The chemical and physical properties of different lipids of body. The clinical part of the work is a prospective randomized comparative controlled clinical trial of patients with atherosclerotic diseases.

Developed the concept of "limited biological resources" of the body based on the increase in the expenditure of energy reserves of the body, allowing a critical look at overweight.

The role of overweight in the development of atheromatous fat was revealed. The positive results from the weight loss in patients with atherosclerotic disease were drawn. Developed the metabolic concept of atherosclerosis associated with evolutionary aging and conversion of lipids in hard atherosclerotic fat.

Inclusion Criteria:

• written informed consent form
• dyslipidemia (HDL <1.0 mmol / l, triglycerides (TG) in plasma ≥ 1,7 mmol / l or cholesterol ≥ 5,6 mmol /l)
• waist circumference ≥ 94.0 cm in men or ≥ 80,0 cm in women,
• BP ≥140/95 mm Hg or a patient is taking antihypertensive medications,
• fasting glucose ≥ 6,1 mmol / l or the patient is taking hypoglycemic agents,
• the possibility of treatment for 6 months and follow-up for 1 year

Exclusion Criteria:

• Absence of consent form
• Non-compliance of patient to necessary recommendations.
• The presence of mental illness.
• Complete immobilization of a patient (paresis, and paralysis).