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The objective is to evaluate therapeutic efficacy of 2 grams nano-phytosterols daily supplemention on diagnosis criteria of metabolic syndrome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Phytosterol | Experimental | Daily consumption of 2 grams (8 ml) nano-phytosterols per 180 days. |
|
| Placebo | Placebo Comparator | Daily consumption of 8 ml of a solution with Titanium Dioxide per 180 days. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Phytosterols | Dietary Supplement | Oral daily consumption of 2 grams of phytosterols (8 ml) per 180 days. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Difference of proportion between study groups in the proportion of metabolic syndrome from baseline and the last visit (180 days). | 180 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universidad de Los Andes | Santiago | Chile |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32785036 | Derived | Palmeiro-Silva YK, Aravena RI, Ossio L, Parro Fluxa J. Effects of Daily Consumption of an Aqueous Dispersion of Free-Phytosterols Nanoparticles on Individuals with Metabolic Syndrome: A Randomised, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2020 Aug 10;12(8):2392. doi: 10.3390/nu12082392. |
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PI will share IPD after doing all possible publications.
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| ID | Term |
|---|---|
| D024821 | Metabolic Syndrome |
| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
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| ID | Term |
|---|---|
| D010840 | Phytosterols |
| C009495 | titanium dioxide |
| ID | Term |
|---|---|
| D013261 | Sterols |
| D002776 | Cholestanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
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| Titanium Dioxide | Dietary Supplement | Oral daily consumption of Titanium Dioxide (8 ml) per 180 days. |
|
| D009750 |
| Nutritional and Metabolic Diseases |
| D011083 |
| Polycyclic Compounds |
| D008563 | Membrane Lipids |
| D008055 | Lipids |
| D064209 | Phytochemicals |
| D001685 | Biological Factors |