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The purpose of this study is to assess the acute effect of dietary fat on satiety and energy metabolism.
The influences of specific dietary fat sources on satiety, appetite and energy utilization remains unclear; evidence is lacking on whether responses vary according to acute intake. The researchers will use a controlled setting to determine whether the source of dietary fat is related to perceived satiety, satiety hormone responses, and energy expenditure by conducting experiments to evaluate short term (acute) effects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Saturated Fat (SFA) | Experimental | 30 grams saturated fat in the form of heavy whipping cream will be provided to subject in a smoothie drink |
|
| Monounsaturated Fat (MUFA) | Experimental | 30 grams monounsaturated fat in the form of high oleic canola oil will be provided to subject in a smoothie drink |
|
| Polyunsaturated Fat Linoleic (PUFA-LA) | Experimental | 30 grams polyunsaturated fat in the form of high linoleic sunflower oil will be provided to subject in a smoothie drink |
|
| Polyunsaturated Fat Alpha-Linolenic (ALA) | Experimental | 30 grams polyunsaturated fat in the form of flaxseed oil will be provided to subject in a smoothie drink |
|
| Polyunsaturated Fat Long Chain Omega-3 (LCn3) | Experimental | 30 grams polyunsaturated fat in the form of fish oil (Coromega Omega3 Squeeze) will be provided to subject in a smoothie drink |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SFA | Other | High saturated fatty acid/SFA oil source |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Acute effect of fat intake on energy expenditure as determined by metabolic rate | Incremental Area Under the Curve (iAUC) of metabolic rate from 0 to 4 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Matthew Picklo, PhD | USDA Grand Forks Human Nutrition Research Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| USDA Grand Forks Human Nutrition Research Center | Grand Forks | North Dakota | 58203 | United States |
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| Label | URL |
|---|---|
| Grand Forks Human Nutrition Research Center Current Nutrition Studies | View source |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| ICF | No | No | Yes | Informed Consent Form | Sep 6, 2019 | Jan 18, 2022 | ICF_000.pdf |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| MUFA |
| Other |
High monounsaturated fatty acid/MUFA oil source |
|
| PUFA-LA | Other | High polyunsaturated fatty acid (linoleic)/PUFA-LA oil source |
|
| ALA | Other | High polyunsaturated fatty acid (alpha-linolenic)/ALA oil source |
|
| LCn3 | Other | High polyunsaturated fatty acid (omega-3)/LCn3 oil source |
|
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |