The purpose of this study is to assess degree of hepatic fibrosis using multiparametric MRI for investigating difference between normal or early fibrosis and advanced fibrosis.

In patients with liver parenchymal disease or normal liver parenchyma who are scheduled to undergo either liver resection or liver biopsy are included.

Referred patients undergo multiparametric MRI including perfusion, diffusion, elastography and fat quantification before surgery or biopsy.

The pathophysiologic changes are evaluated using multiparametric MRI, and compared between normal/early fibrosis and advanced fibrosis.

Inclusion Criteria:

• patients who are scheduled to undergo liver resection for focal liver lesion
• patients who are scheduled to undergo liver resection or percutaneous biopsy for diffuse parenchymal disease
• liver donor candidate who are scheduled to undergo preoperative liver biopsy or liver resection
• AND patients/living donor candidates who sign informed consent

Exclusion Criteria: Patients who have at least one of followings are excluded.

• Patients who are contraindication for MRI contrast enhanced MRI.
• Premenopausal female patients who are pregnant.
• Patients who are physically compromised to acquire liver MRI