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| Name | Class |
|---|---|
| GE Healthcare | INDUSTRY |
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As cirrhosis progresses, alteration of hemodynamics develops and decreased portal flow is often observed. Since direct measurement of portal pressure (HVPG) is invasive, non-invasive methods have drawn a lot of attention. MRI is one of the non-invasive methods and it is able to provide multiparametric data in one examination. Herein, we evaluate hepatic fibrosis with different stage using multiparametric MRI with emphasis on portal flow measurement.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Liver MRI | Experimental | Liver MRI including noncontrast (precontrast) flow measurement, DCE, DWI using multiple b-values, MRE and MR fat quantification. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Liver MRI | Diagnostic Test | Multiparametric Liver MRI including following sequences: DCE, DWI, MRE, precontrast flow measurement, fat quantification. |
|
| Measure | Description | Time Frame |
|---|---|---|
| hepatic fibrosis stage | F0-1 vs. F2-4 using multiparametric MRI | 1 month after MRI |
| Measure | Description | Time Frame |
|---|---|---|
| presence of varix | presence of esophageal or gastric varices using multiparametric MRI | 1 month after MRI |
| comparison of portal flow measurement | comparison of portal flow measurement using DCE and precontrast flow measurement |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jeong Min Lee, MD | Seoul National University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | South Korea |
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| ID | Term |
|---|---|
| D005355 | Fibrosis |
| D006505 | Hepatitis |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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| 1 month after MRI |